ArticleFrontiers in immunology2020
Erratum issuedAbstract read
In one paragraph
Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 53 papers.
0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed.
- What is in the Dust? Species-Level Profiling Reveals Pathogenic and Protective Potential of Microbial Communities in Daycare and Home Environments.Environmental microbiology reports · 2026Article
- A human ex vivo model of radiation-induced skin injury recapitulates p53-driven profibrotic response to radiotherapy.JCI insight · 2026Article
- A bioelectric dressing improves postderoofing outcomes in hidradenitis suppurativa by microbiome modulation: A split-body, randomized clinical trial.JID innovations : skin science from molecules to population health · 2026Article
- Development of an ex vivo skin model for quantitative recovery and preservation of donor-specific human microbiota.BMC microbiology · 2026Article
- The human breast milk microbiome: a landscape review of its composition, origins, and impact on infant health.Archives of microbiology · 2026Review
- Genetic modification of intractable bacterial clones by heat shock-facilitated phage transduction.Cell reports methods · 2026Article
- Targeting polymicrobial skin infections in atopic dermatitis: role ofFrontiers in microbiology · 2026Article
- Emerging Microbiome-Based Therapies for Skin Infections: From Probiotics and Prebiotics to Synthetic Microbiome Engineering.Infection and drug resistance · 2026Review
- Dynamic remodeling of skin microbiota during healthy homeostatic and wound repair conditions.Frontiers in microbiology · 2026Review
- Herbal polysaccharides-a rising star in engineering multifunctional biomaterials for tissue repair and regeneration.Regenerative biomaterials · 2026Review
- Interaction BetweenCurrent pharmaceutical biotechnology · 2026Review
- Microbial allies in skin trauma recovery: from immune modulation to engineered probiotic therapeutics.Burns & trauma · 2026Review
- Postbiotics as microbial-derived therapeutics for wound healing disorders: from molecular mechanisms to future application.Cell communication and signaling : CCS · 2025Review
- Wounds and the Microbiota: The Healing Interplay Between Host and Microbial Communities.International journal of molecular sciences · 2025Review
- Enhancing melanoma treatment through systemic delivery of an immune boosting Staphylococcus epidermidis strain.Scientific reports · 2025Article
- Metabolites derived from bacterial isolates of the human skin microbiome inhibitMicrobiology spectrum · 2025Article
- What's New in Wound Healing: Treatment Advances and Microbial Insights.American journal of clinical dermatology · 2025Review
- Clinical profiling of skin microbiome and metabolome during re-epithelialization.Scientific reports · 2025Article
- Skin Microbiome and Radiation-Induced Skin Injury: Unraveling the Relationship, Mechanisms, and Therapeutic Implications.International journal of molecular sciences · 2025Review
- Skin microbiome influences the progression of cutaneous squamous cell carcinoma through the immune system.World journal of surgical oncology · 2025Review
Corrections and comments
- Erratum issuedCorrigendum:2021
Authors and funding
13 authors.
Irena PastarWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States.
Katelyn O'NeillDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.
Laura PadulaDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.
Cheyanne R HeadWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States.
Jamie L BurgessWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States.
Vivien ChenWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States.
Denisse GarciaDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.
Olivera StojadinovicWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States.
Suzanne HowerDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.
Gregory V PlanoDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.
Seth R ThallerDivision of Plastic Surgery Dewitt Daughtry, Department of Surgery, University of Miami Miller School of Medicine, Miami, FL, United States.
Marjana Tomic-CanicWound Healing and Regenerative Medicine Research Program, Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, United States.
Natasa StrboDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.
Funding
Perforin-2: The role of a novel antimicrobial protein in diabetic foot ulcersR01NR015649 · NINR · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI STRBO, NATASA, TOMIC-CANIC, MARJANA · 2015 to 2019
$2.6MMedical Scientist Training ProgramT32GM112601 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI LEMMON, SANDRA K. · 2017 to 2021
$1.9MUniversity of Miami Clinical Research Unit of the Diabetic Foot ConsortiumU01DK119085 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI KIRSNER, ROBERT SCOTT, LEV-TOV, HADAR · 2018 to 2022
$1.8MMicro-RNA Molecules as Regulators of Diabetic Wound HealingR01NR013881 · NINR · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI TOMIC-CANIC, MARJANA · 2012 to 2015
$1.7MDevelopment of the Cellular Biomarker for Diabetic Foot UlcersRC1DK086364 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BREM, HAROLD, TOMIC-CANIC, MARJANA · 2009 to 2010
$903kNIDDK NIH HHS RC1 DK086364NIDDK NIH HHS U01 DK119085NIGMS NIH HHS T32 GM112601NINR NIH HHS R01 NR013881NINR NIH HHS R01 NR015649
Abstract
Perforin-2 (P-2) is an antimicrobial protein with unique properties to kill intracellular bacteria. Gamma delta (GD) T cells, as the major T cell population in epithelial tissues, play a central role in protective and pathogenic immune responses in the skin. However, the tissue-specific mechanisms that control the innate immune response and the effector functions of GD T cells, especially the cross-talk with commensal organisms, are not very well understood. We hypothesized that the most prevalent skin commensal microorganism,
Indexed as
Immunity, InnateBiomarkersCytokinesCytotoxicity, ImmunologicFibroblastsGene Expression RegulationHost-Pathogen InteractionsHumansImmunomodulationInflammation MediatorsKeratinocytesLymphocyte ActivationLymphocyte CountPore Forming Cytotoxic ProteinsReceptors, Antigen, T-Cell, gamma-deltaStaphylococcal Skin InfectionsBiomarkersCytokinesInflammation Mediatorsperforin 2Pore Forming Cytotoxic ProteinsReceptors, Antigen, T-Cell, gamma-deltacytotoxicitygamma delta T cellshuman skininnate immunityperforin-2/mpeg-1Staphylococcus epidermidis
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.