Evidence map›Paper›PMID 33042001›Full record

ArticleFrontiers in endocrinology2020

Acute Phase Serum Leptin, Adiponectin, Interleukin-6, and Visfatin Are Altered in Chinese Children With Febrile Seizures: A Cross-Sectional Study.

Jie-Ru Chen, Mei-Fang Jin, Ling Tang, Yue-Ying Liu, Hong Ni

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jie-Ru ChenDivision of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China.
Mei-Fang JinDivision of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China.
Ling TangWuxi Second People's Hospital, Wuxi, China.
Yue-Ying LiuDivision of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China.
Hong NiDivision of Brain Science, Institute of Pediatric Research, Children's Hospital of Soochow University, Suzhou, China.
Soochow University · CNWuxi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipokines, including leptin, visfatin, adiponectin, and interleukin-6 (IL)-6, play multiple roles in the pathophysiology of epilepsy and febrile seizures (FS). We aimed to investigate the associations among plasma adipokines, mainly leptin, visfatin, adiponectin, or IL-6, and the prognosis of FS. This prospective cross-sectional study was conducted from January 2017 to December 2018 at the Wuxi Second People' Hospital China. The levels of serum leptin, visfatin, adiponectin, and IL-6 in 55 children with FS (FS group) were compared with 42 febrile children without seizure (FC group) and 48 healthy children (HC group) in an acute phase. The correlation with clinical indicators was determined by logistic regression analysis. Serum adiponectin and IL-6 levels were significantly higher in the FS group than in the FC and HC groups (

Indexed as

AdiponectinBiomarkersCase-Control StudiesChildChild, PreschoolCross-Sectional StudiesCytokinesFemaleHumansInfantInterleukin-6LeptinMaleNicotinamide PhosphoribosyltransferasePrognosisProspective StudiesAdiponectinADIPOQ protein, humanBiomarkersCytokinesIL6 protein, humanInterleukin-6LeptinNicotinamide Phosphoribosyltransferasenicotinamide phosphoribosyltransferase, humanadiponectinfebrile seizuresIL-6leptinvisfatin

Identifiers

PMID33042001
PMCPMC7522506
OpenAlexW3092519912

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.