ArticleFrontiers in psychology2020
Microstructural Integrity of the Hippocampus During Childhood: Relations With Age and Source Memory.
Article in Frontiers in psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Sleep forms flexible context representations in toddlers.Nature communications · 2026Article
- Trajectories of hippocampal subregion development in the first years of life and their association with school-aged episodic memory outcomes.bioRxiv : the preprint server for biology · 2026Article
- Microstructural variation of hippocampal substructures across childhood and adolescence quantified with high-gradient diffusion MRI.Communications biology · 2026Article
- Independent associations of sleep and physical activity with cognition are mediated by hippocampal microstructure in middle-aged and older adults.Neurobiology of aging · 2025Article
- Axial and mean diffusivity predict myelin density in the hippocampus of pigs during early brain development, independent of sex.Frontiers in neuroscience · 2025Article
- The developing hippocampus: Microstructural evolution through childhood and adolescence.bioRxiv : the preprint server for biology · 2024Article
- Acute cycling exercise and hippocampal subfield function and microstructure in healthy older adults.Hippocampus · 2023Article
- Development of human hippocampal subfield microstructure and relation to associative inference.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Alterations in Human Hippocampus Subregions across the Lifespan: Reflections on White Matter Structure and Functional Connectivity.Neural plasticity · 2023Article
- Intraobject and extraobject memory binding across early development.Developmental psychology · 2022Article
- Neurite dispersion and density mediates the relationship between cardiorespiratory fitness and cognition in healthy younger adults.Neuropsychologia · 2022Article
- Article
- Exercise Training-Related Changes in Cortical Gray Matter Diffusivity and Cognitive Function in Mild Cognitive Impairment and Healthy Older Adults.Frontiers in aging neuroscience · 2021Article
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3 authors.
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Abstract
The hippocampus is a brain structure known to be important for memory. However, studies examining relations between hippocampal volume and memory across development yield mixed results. This may be due in part to the fact that volume is a coarser measure of hippocampal composition. Studies have begun to examine measures of diffusion, which capture characteristics of the microstructure of the hippocampus, and thus may provide additional information about the integrity of the underlying neural circuits. The present study applied this approach to a developmental period characterized by dramatic changes in both hippocampal microstructure and memory behavior - early childhood. Specifically, measures of hippocampal microstructural integrity were related to age and source memory performance in 93 children aged 4-8 years. Results revealed significant negative associations between hippocampal mean diffusivity and both age and memory, even after controlling for differences in hippocampal volume. These results suggest that hippocampal diffusion may provide additional, independent information about hippocampal integrity compared to volume, particularly during early childhood when important developmental changes have been proposed.
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