ArticleFrontiers in physiology2020
Association of Alcohol Intake and Semen Parameters in Men With Primary and Secondary Infertility: A Cross-Sectional Study.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Targeting Modifiable Risks: Molecular Mechanisms and Population Burden of Lifestyle Factors on Male Genitourinary Health.International journal of molecular sciences · 2025Pooled it
- Comparative Assessment of Manual Versus Automated Semen Analysis and the Role of Novel Biomarker Calprotectin in Screening for Male Factor Infertility.Iranian journal of pathology · 2026Article
- Association of Ureaplasma urealyticum with lifestyle factors and semen parameters: results from a cross-sectional study in 2668 males.Asian journal of andrology · 2026Article
- Alcohol alters blood-testis barrier function in an in vitro model.F&S science · 2025Article
- Male Fertility as a Proxy for Health.Journal of clinical medicine · 2024Review
- Mendelian randomization reveals the impact of diet on infertility in men and women.Frontiers in endocrinology · 2024Article
- The nutritional content required to design an educational application for infertile women.BMC women's health · 2023Article
- Is seminal quality worsening? A 20-year experience in Córdoba, Argentina.Journal of assisted reproduction and genetics · 2022Article
- The efficacy and mechanism of acupuncture in the treatment of male infertility: A literature review.Frontiers in endocrinology · 2022Review
- Impact of Alcohol Consumption on Male Fertility Potential: A Narrative Review.International journal of environmental research and public health · 2021Review
- Do aging, drinking, and having unhealthy weight have a synergistic impact on semen quality?Journal of assisted reproduction and genetics · 2021Article
- Association between semen collection time and semen parameters: an observational study.Asian journal of andrologyObservational
- Association of sexually transmitted infection with semen quality in men from couples with primary and secondary infertility.Asian journal of andrologyArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alcohol consumption has commonly been associated with semen parameters. However, the association between alcohol intake and semen parameters in primary and secondary infertile men remains unclear. In this study, 776 infertile men from China were grouped according to alcohol intake: abstainers, moderate drinkers (<9 units/week, up to approximately 100 g of ethanol) and heavy drinkers (≥9 units/week). Semen parameters, including semen volume, sperm concentration, total sperm count, progressive motility and normal morphology were investigated. Alcohol consumption and other lifestyle factors were assessed by questionnaire. Logistic regression models were applied. There was no significant association between alcohol consumption and semen parameters in men with primary infertility. Smaller testis volumes and lower sperm concentrations were found among moderate and heavy drinkers in the secondary infertility group than among abstainers. After adjustment for potential confounders, men with secondary infertility and heavy alcohol consumption had a higher risk of abnormal sperm concentrations (OR = 3.72; 95% CI, 1.04, 13.37). These findings suggest that alcohol intake may decrease sperm concentrations in men with secondary infertility, whereas no association was found in men with primary infertility. It may be beneficial for clinicians to advise male patients with secondary infertility who are seeking fertility treatment to avoid heavy alcohol consumption.
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