ArticleFrontiers in physiology2020
Cardiorespiratory and Neuromuscular Demand of Daily Centrifugation: Results From the 60-Day AGBRESA Bed Rest Study.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- The effect of artificial gravity on the outcome of a two-week resistance vibration exercise programme: BRAVE study.Experimental physiology · 2026Article
- The combined effects of artificial gravity, temperature, and hypoxia on haemodynamic responses and limb blood flow.European journal of applied physiology · 2025Article
- Effect of artificial gravity on neurocognitive performance during head-down tilt bedrest.NPJ microgravity · 2024Article
- Human gut microbiome and metabolite dynamics under simulated microgravity.Gut microbes · 2023Article
- Environmental enrichment through virtual reality as multisensory stimulation to mitigate the negative effects of prolonged bed rest.Frontiers in aging neuroscience · 2023Review
- Optic disc edema during strict 6° head-down tilt bed rest is related to one-carbon metabolism pathway genetics and optic cup volume.Frontiers in ophthalmology · 2023Article
- A comparison between left ventricular ejection time measurement methods during physiological changes induced by simulated microgravity.Experimental physiology · 2022Article
- Cardiovascular deconditioning and impact of artificial gravity during 60-day head-down bed rest-Insights from 4D flow cardiac MRI.Frontiers in physiology · 2022Article
- Assessing the effects of artificial gravity in an analog of long-duration spaceflight: The protocol and implementation of the AGBRESA bed rest study.Frontiers in physiology · 2022Article
- Comparison of trunk muscle exercises in supine position during short arm centrifugation with 1 g at centre of mass and upright in 1 g.Frontiers in physiology · 2022Article
- Limited Effect of 60-Days Strict Head Down Tilt Bed Rest on Vascular Aging.Frontiers in physiology · 2021Article
- The Effects of Long Duration Spaceflight on Sensorimotor Control and Cognition.Frontiers in neural circuits · 2021Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeLong stays in space require countermeasures for the degrading effects of weightlessness on the human body, and artificial gravity (AG) has been proposed as an integrated countermeasure. The aim of this study was to assess the cardiorespiratory and neuromuscular demand of AG elicited via daily centrifugation during 60 days of bed rest.
methodsTwenty four participants (33 ± 9 y, 175 ± 9 cm, 74 ± 10 kg, 8 female) were subjected to 60 days of strict six-degree head-down tilt (HDT) bed rest and were randomly allocated to one of three experimental groups: 30 min of daily centrifugation with an acceleration of 1 g at the center of mass and 2 g at the feet applied continuously (cAG) or intermittently in 6 epochs of 5 min each, separated by 3 min breaks (iAG), or non-centrifuged control (CTRL). Cardiorespiratory demand during centrifugation was assessed at the beginning (HDT3) and end (HDT60) of the bed rest phase via spirometry and heart rate monitoring, leg muscle activation was monitored via electromyography.
resultsOn average, analyses of variance revealed that heart rate during centrifugation increased by 40% (iAG) and 60% (cAG) compared to resting values (
conclusionDaily 30 min bouts of artificial gravity elicited by centrifugation put a substantial demand on the heart as a pump without increasing oxygen consumption. If centrifugation is to be used as a countermeasure for the deteriorating effects of microgravity on physical performance, we recommend combining it with strenuous exercise.
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