Evidence map›Paper›PMID 33041858›Full record

ArticleFrontiers in physiology2020

Using Electrical Impedance Myography as a Biomarker of Muscle Deconditioning in Rats Exposed to Micro- and Partial-Gravity Analogs.

Carson Semple, Daniela Riveros, Dong-Min Sung, Janice A Nagy, Seward B Rutkove, Marie Mortreux

Abstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  12. The individual and combined effects of spaceflight radiation and microgravity on biologic systems and functional outcomes.Journal of environmental science and health. Part C, Toxicology and carcinogenesis · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carson SempleDepartment of Neurology, Harvard Medical School - Beth Israel Deaconess Medical Center, Boston, MA, United States.
Daniela RiverosDepartment of Neurology, Harvard Medical School - Beth Israel Deaconess Medical Center, Boston, MA, United States.
Dong-Min SungDepartment of Neurology, Harvard Medical School - Beth Israel Deaconess Medical Center, Boston, MA, United States.
Janice A NagyDepartment of Neurology, Harvard Medical School - Beth Israel Deaconess Medical Center, Boston, MA, United States.
Seward B RutkoveDepartment of Neurology, Harvard Medical School - Beth Israel Deaconess Medical Center, Boston, MA, United States.
Marie MortreuxDepartment of Neurology, Harvard Medical School - Beth Israel Deaconess Medical Center, Boston, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As astronauts prepare to undertake new extra-terrestrial missions, innovative diagnostic tools are needed to better assess muscle deconditioning during periods of weightlessness and partial gravity. Electrical impedance myography (EIM) has been used to detect muscle deconditioning in rodents exposed to microgravity during spaceflight or using the standard ground-based model of hindlimb unloading via tail suspension (HU). Here, we used EIM to assess muscle changes in animals exposed to two new models: hindlimb suspension using a pelvic harness (HLS) and a partial weight-bearing (PWB) model that mimics partial gravity (including Lunar and Martian gravities). We also used a simple needle array electrode in lieu of surface or

Indexed as

EIMground-basedhindlimb unloadingimpedancemusclepartial weight-bearingratsspaceflight

Identifiers

PMID33041858
PMCPMC7522465

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.