Evidence map›Paper›PMID 33041855›Full record

ArticleFrontiers in physiology2020

Effect of Hyperventilation on Periodic Repolarization Dynamics.

Dominik Schüttler, Lukas von Stülpnagel, Konstantinos D Rizas, Axel Bauer, Stefan Brunner, Wolfgang Hamm

Abstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dominik SchüttlerMedizinische Klinik und Poliklinik I, University Hospital Munich, Ludwig-Maximilians University Munich (LMU), Munich, Germany.
Lukas von StülpnagelMedizinische Klinik und Poliklinik I, University Hospital Munich, Ludwig-Maximilians University Munich (LMU), Munich, Germany.
Konstantinos D RizasMedizinische Klinik und Poliklinik I, University Hospital Munich, Ludwig-Maximilians University Munich (LMU), Munich, Germany.
Axel BauerDZHK (German Centre for Cardiovascular Research), Partner Site Munich, Munich Heart Alliance (MHA), Munich, Germany.
Stefan BrunnerMedizinische Klinik und Poliklinik I, University Hospital Munich, Ludwig-Maximilians University Munich (LMU), Munich, Germany.
Wolfgang HammMedizinische Klinik und Poliklinik I, University Hospital Munich, Ludwig-Maximilians University Munich (LMU), Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart and lung functions are closely connected, and the interaction is mediated by the autonomic nervous system. Hyperventilation has been demonstrated to especially activate its sympathetic branch. However, there is still a lack of methods to assess autonomic activity within this cardiorespiratory coupling. Periodic repolarization dynamics (PRD) is an ECG-based biomarker mirroring the effect of efferent cardiac sympathetic activity on the ventricular myocardium. Its calculation is based on beat-to-beat variations of the T wave vector (

Indexed as

autonomic functionhyperventilationperiodic repolarization dynamicsrepolarization instabilitysympathetic nervous systemT wave vector

Identifiers

PMID33041855
PMCPMC7530251

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.