Evidence map›Paper›PMID 33041781›Full record

ReviewFrontiers in pharmacology2020

Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications.

Javad Sharifi-Rad, Youssef El Rayess, Alain Abi Rizk, Carmen Sadaka, Raviella Zgheib, Wissam Zam, Simona Sestito, Simona Rapposelli, Katarzyna Neffe-Skocińska, Dorota Zielińska and 11 more

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05896878 (The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients), which is not on this map. Cited by 344 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
344citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05896878 naterminatednot on this mapstarted 2023, after this paper: background citation

The Effects of Daily Anti-inflammatory Supplementation on Foundation Pain Index Scores in Chronic Opiate Patients

TypeinterventionalSponsorHudson MedicalRan2023 to 2024Enrolled1ConditionsPain, Chronic, Opioid Dependence, Opioid Use, Inflammation ChronicArmsRoot.Health Dietary Supplement
3 · Its place in the literature

Who cites it

344 citing papers in PubMed, 15 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Trial
  17. Curcumin enhances the oral bioavailability of testosterone by inhibiting its intestinal metabolism.Drug metabolism and disposition: the biological fate of chemicals · 2025
    Trial
  18. Trial
  19. Turmeric (Pharmaceutical biology · 2026
    Review
  20. Article

284 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Javad Sharifi-RadZabol Medicinal Plants Research Center, Zabol University of Medical Sciences, Zabol, Iran.
Youssef El RayessDepartment of Agriculture and Food Engineering, School of Engineering, Holy Spirit University of Kasli, Jounieh, Lebanon.
Alain Abi RizkDepartment of Agriculture and Food Engineering, School of Engineering, Holy Spirit University of Kasli, Jounieh, Lebanon.
Carmen SadakaFaculty of Medicine, American University of Beirut, Beirut, Lebanon.
Raviella ZgheibInstitut Jean-Pierre Bourgin, AgroParisTech, INRA, Université Paris-Saclay, Versailles, France.
Wissam ZamDepartment of Analytical and Food Chemistry, Faculty of Pharmacy, Al-Andalus University for Medical Sciences, Tartous, Syria.
Simona SestitoDepartment of Pharmacy, University of Pisa, Pisa, Italy.
Simona RapposelliDepartment of Pharmacy, University of Pisa, Pisa, Italy.
Katarzyna Neffe-SkocińskaInstitute of Human Nutrition Sciences, Warsaw University of Life Sciences, Warszawa, Poland.
Dorota ZielińskaInstitute of Human Nutrition Sciences, Warsaw University of Life Sciences, Warszawa, Poland.
Bahare SalehiNoncommunicable Diseases Research Center, Bam University of Medical Sciences, Bam, Iran.
William N SetzerAromatic Plant Research Center, Lehi, UT, United States.
Noura S DosokyAromatic Plant Research Center, Lehi, UT, United States.
Yasaman TaheriPhytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Marc El BeyrouthyDepartment of Agriculture and Food Engineering, School of Engineering, Holy Spirit University of Kasli, Jounieh, Lebanon.
Miquel MartorellDepartment of Nutrition and Dietetics, Faculty of Pharmacy, University of Concepcion, Concepcion, Chile.
Elise Adrian OstranderMedical Illustration, Kendall College of Art and Design, Ferris State University, Grand Rapids, MI, United States.
Hafiz Ansar Rasul SuleriaDepartment of Agriculture and Food Systems, The University of Melbourne, Melbourne, VIC, Australia.
William C ChoDepartment of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong.
Alfred MaroyiDepartment of Botany, University of Fort Hare, Alice, South Africa.
Natália MartinsFaculty of Medicine, University of Porto, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Curcumin, a yellow polyphenolic pigment from the

Indexed as

biotechnological applicationscurcumaCurcuma longa L.curcuminoidspharmacological effectsspiceturmeric

Identifiers

PMID33041781
PMCPMC7522354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.