ArticleAdvanced functional materials2020
Hybrid 3D Printing of Synthetic and Cell-Laden Bioinks for Shape Retaining Soft Tissue Grafts.
Article in Advanced functional materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed.
- Large-scale manufacturing of precisely patterned flexible soft tissue implants with high porosity.Biofabrication · 2026Article
- Toward 4D printed functional soft tissues.Acta biomaterialia · 2026Review
- Functional personalization in digital manufacturing: a translational framework for patient-specific implants, arthroscopic locators, and therapeutic constructs.Frontiers in bioengineering and biotechnology · 2026Article
- 3D bioprinting of cell-laden constructs: technologies, bioink design, and biomedical applications.Biomedical materials (Bristol, England) · 2025Review
- Conjugation of Proangiogenic Peptide to Enhance a Soft Tissue Bioink.Journal of biomedical materials research. Part A · 2025Article
- Integrated biomimetic bioprinting of perichondrium with cartilage for auricle reconstruction.Bioactive materials · 2025Article
- Mechanically robust non-swelling cold water fish gelatin hydrogels for 3D bioprinting.Materials today. Bio · 2025Article
- The application of tissue engineering strategies for uterine regeneration.Materials today. Bio · 2025Review
- Bioprinting approaches in cardiac tissue engineering to reproduce blood-pumping heart function.iScience · 2025Review
- 3D bioprinting patient-specific grafts for tendon/ligament repair in motion: emerging trends and challenges.Frontiers in bioengineering and biotechnology · 2025Review
- Development and Characterization of Heparin-Containing Hydrogel/3D-Printed Scaffold Composites for Craniofacial Reconstruction.Annals of biomedical engineering · 2024Article
- Advancements in Tissue Engineering: A Review of Bioprinting Techniques, Scaffolds, and Bioinks.Biomedical engineering and computational biology · 2024Review
- Manufacture Dependent Differential Biodegradation of 3D Printed Shape Memory Polymers.Virtual and physical prototyping · 2024Article
- Clinical Applicability of Visible Light-Mediated Cross-linking for Structural Soft Tissue Reconstruction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Cold plasma treatment to improve jelly production using a fused deposition modeling 3D printer.Food science and biotechnology · 2023Article
- Chitin nanocrystal-assisted 3D bioprinting of gelatin methacrylate scaffolds.Regenerative biomaterials · 2023Article
- Microtissue-Based Bioink as a Chondrocyte Microshelter for DLP Bioprinting.Advanced healthcare materials · 2022Article
- Bioprinting and regeneration of auricular cartilage using a bioactive bioink based on microporous photocrosslinkable acellular cartilage matrix.Bioactive materials · 2022Article
- Biostimulatory Micro-Fragmented Nanofiber-Hydrogel Composite Improves Mesenchymal Stem Cell Delivery and Soft Tissue Remodeling.Small (Weinheim an der Bergstrasse, Germany) · 2022Article
- Computational investigation of interface printing patterns within 3D printed multilayered scaffolds for osteochondral tissue engineering.Biofabrication · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Despite recent advances in clinical procedures, the repair of soft tissue remains a reconstructive challenge. Current technologies such as synthetic implants and dermal flap autografting result in inefficient shape retention and unpredictable aesthetic outcomes. 3D printing, however, can be leveraged to produce superior soft tissue grafts that allow enhanced host integration and volume retention. Here, a novel dual bioink 3D printing strategy is presented that utilizes synthetic and natural materials to create stable, biomimetic soft tissue constructs. A double network ink composed of covalently crosslinked poly(ethylene) glycol and ionically crosslinked alginate acts as a physical support network that promotes cell growth and enables long-tersm graft shape retention. This is coupled with a cell-laden, biodegradable gelatin methacrylate bioink in a hybrid printing technique, and the composite scaffolds are evaluated in their mechanical properties, shape retention, and cytotoxicity. Additionally, a new shape analysis technique utilizing CloudCompare software is developed that expands the available toolbox for assessing scaffold aesthetic properties. With this dynamic 3D bioprinting strategy, complex geometries with robust internal structures can be easily modulated by varying the print ratio of non-degradable to sacrificial strands. The versatility of this hybrid printing fabrication platform can inspire the design of future multi-material regenerative implants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.