ArticleAnnual reviews in control2020
Characterization of SARS-CoV-2 dynamics in the host.
Article in Annual reviews in control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 1 citations in OpenAlex.
- Design principles of the cytotoxic CD8Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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- Design principles of the cytotoxic CD8bioRxiv : the preprint server for biology · 2025Article
- Multi-objective control to schedule therapies for acute viral infections.Journal of mathematical biology · 2025Article
- A theory for viral rebound after antiviral treatment: A study case for SARS-CoV-2.Mathematical biosciences · 2025Article
- A biomathematical model of SARS-CoV-2 in Syrian hamsters.Scientific reports · 2024Article
- Understanding antibody magnitude and durability following vaccination against SARS-CoV-2.Mathematical biosciences · 2024Article
- Review
- Confinement tonicity on epidemic spreading.Journal of mathematical biology · 2024Article
- Topological data analysis of antibody dynamics of severe and non-severe patients with COVID-19.Mathematical biosciences · 2023Article
- Simplified within-host and Dose-response Models of SARS-CoV-2.Journal of theoretical biology · 2023Article
- Stability of a delayed SARS-CoV-2 reactivation model with logistic growth and adaptive immune response.Physica A · 2023Article
- The race to understand immunopathology in COVID-19: Perspectives on the impact of quantitative approaches to understand within-host interactions.Immunoinformatics (Amsterdam, Netherlands) · 2023Review
- Minimizing the epidemic final size while containing the infected peak prevalence in SIR systems.Automatica : the journal of IFAC, the International Federation of Automatic Control · 2022Article
- Differential evolution and particle swarm optimization against COVID-19.Artificial intelligence review · 2022Article
- Effectiveness of Antiviral Therapy in Highly-Transmissible Variants of SARS-CoV-2: A Modeling and Simulation Study.Frontiers in pharmacology · 2022Article
- Characterizing viral within-host diversity in fast and non-equilibrium demo-genetic dynamics.Frontiers in microbiology · 2022Article
- The dominant strain of SARS-CoV-2 is a mosaicism.Virus research · 2021Article
- Corticosteroid therapy for 2019-nCoV-infected patients: A case series of eight mechanically ventilated patients.Clinical case reports · 2021Article
- Current and prospective computational approaches and challenges for developing COVID-19 vaccines.Advanced drug delivery reviews · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While many epidemiological models were proposed to understand and handle COVID-19 pandemic, too little has been invested to understand human viral replication and the potential use of novel antivirals to tackle the infection. In this work, using a control theoretical approach, validated mathematical models of SARS-CoV-2 in humans are characterized. A complete analysis of the main dynamic characteristic is developed based on the reproduction number. The equilibrium regions of the system are fully characterized, and the stability of such regions is formally established. Mathematical analysis highlights critical conditions to decrease monotonically SARS-CoV-2 in the host, as such conditions are relevant to tailor future antiviral treatments. Simulation results show the aforementioned system characterization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.