Evidence map›Paper›PMID 33041191›Full record

ArticleRevista iberoamericana de micologia

Fungal co-infection in COVID-19 patients: Should we be concerned?

Javier Pemán, Alba Ruiz-Gaitán, Carolina García-Vidal, Miguel Salavert, Paula Ramírez, Francesc Puchades, Marta García-Hita, Ana Alastruey-Izquierdo, Guillermo Quindós

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Revista iberoamericana de micologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 7 pooled it
4.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 7 syntheses or guidelines pooled it, 194 citations in OpenAlex.

  1. Pooled it
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  8. Review
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  10. Article
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  15. Managing Invasive Fungal Infections During Allogeneic Hematopoietic Transplantation: A 2025 Update.Mediterranean journal of hematology and infectious diseases · 2025
    Review
  16. Review
  17. Article
  18. Journal of fungi (Basel, Switzerland) · 2024
    Article
  19. Article
  20. COVID-19 reduces immune competence and precipitates superinfections.Journal of family medicine and primary care · 2024
    Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Javier PemánServicio de Microbiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain; Instituto de Investigación Sanitaria La Fe, Valencia, Spain. Electronic address: javier.peman@gmail.com.
Alba Ruiz-GaitánInstituto de Investigación Sanitaria La Fe, Valencia, Spain.
Carolina García-VidalServicio de Enfermedades Infecciosas, Hospital Clínic, Barcelona, Spain.
Miguel SalavertInstituto de Investigación Sanitaria La Fe, Valencia, Spain; Unidad de Enfermedades Infecciosas, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Paula RamírezServicio de Medicina Intensiva, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Francesc PuchadesServicio de Medicina Interna, Consorci Hospital General Universitari, Valencia, Spain.
Marta García-HitaServicio de Microbiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain.
Ana Alastruey-IzquierdoLaboratorio de Referencia e Investigación en Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Guillermo QuindósDepartamento de Inmunología, Microbiología y Parasitología, Facultad de medicina y Enfermería, Universidad del País Vasco/Euskal Herriko Unibertsitatea (UPV/EHU), Spain.
Hospital Universitari i Politècnic La Fe · ESHospital Clínic de Barcelona · ESHospital General Universitario De Valencia · ESInstituto de Investigación Sanitaria La Fe · ESInstituto de Salud Carlos III · ESUniversity of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Critically ill COVID-19 patients have higher pro-inflammatory (IL-1, IL-2, IL-6, tumor necrosis alpha) and anti-inflammatory (IL-4, IL-10) cytokine levels, less CD

Indexed as

BetacoronavirusCandidiasis, InvasiveCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCoinfectionCoronavirus InfectionsCOVID-19HumansInterferon-gammaInterleukinsInvasive Pulmonary AspergillosisPandemicsPneumonia, PneumocystisPneumonia, ViralSARS-CoV-2SpainInterferon-gammaInterleukinsTumor Necrosis Factor-alphaAspergillosisAspergilosisCandidiasisCoinfección fúngicaCOVID-19Fungal coinfectionInvasive mycosesMicosis invasivaNeumocistosisPneumocystosisSARS-CoV-2

Identifiers

PMID33041191
PMCPMC7489924
OpenAlexW3085522385

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.