ArticleAmerican journal of preventive medicine2021
Predictive Factors for a New Positive Nasopharyngeal Swab Among Patients Recovered From COVID-19.
Article in American journal of preventive medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Prevalence, risk factors and treatments for post-COVID-19 breathlessness: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Long COVID-19: The Need for an Interdisciplinary Approach.Clinics in geriatric medicine · 2022Pooled it
- Fatigue Symptoms Associated With COVID-19 in Convalescent or Recovered COVID-19 Patients; a Systematic Review and Meta-Analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2022Pooled it
- Frequency, signs and symptoms, and criteria adopted for long COVID-19: A systematic review.International journal of clinical practice · 2021Pooled it
- Pooled it
- Ultrasensitive detection of intact SARS-CoV-2 particles in complex biofluids using microfluidic affinity capture.Science advances · 2025Article
- Post-COVID-19 and Irritable Bowel Syndrome: A Literature Review.Medicina (Kaunas, Lithuania) · 2023Review
- Evaluating Policies to Decrease the Risk of Introducing SARS-CoV-2 Infections to Nursing Home Facilities.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023Article
- Estimate of undetected severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection in acute-care hospital settings using an individual-based microsimulation model.Infection control and hospital epidemiology · 2023Article
- Corrigendum to "The prevalence and long-term health effects of long Covid among hospitalised and non-hospitalised populations: a systematic review and meta-analysis".EClinicalMedicine · 2023Article
- Dynamics of Anti-S IgG Antibodies Titers after the Second Dose of COVID-19 Vaccines in the Manual and Craft Worker Population of Qatar.Vaccines · 2023Article
- Characteristics of patients with SARS-COV-2 PCR re-positivity after recovering from COVID-19.Epidemiology and infection · 2023Article
- What might COVID-19 patients experience after recovery? A comprehensive review.The International journal of pharmacy practice · 2022Review
- Symptomatology and microbiology of the gastrointestinal tract in post-COVID conditions.JGH open : an open access journal of gastroenterology and hepatology · 2022Review
- Quality of life and persistence of COVID-19 symptoms 90 days after hospital discharge.The Journal of international medical research · 2022Article
- Observational
- The Correlation Between Triglyceride-Glucose Index and SARS-CoV-2 RNA Re-Positive in Discharged COVID-19 Patients.Infection and drug resistance · 2022Article
- Practical management of patients with hematological diseases during the COVID-19 pandemic in Japan.International journal of hematology · 2021Article
- On forecasting the community-level COVID-19 cases from the concentration of SARS-CoV-2 in wastewater.The Science of the total environment · 2021Article
- The COVID-19 Menace.Global challenges (Hoboken, NJ) · 2021Review
Corrections and comments
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Authors and funding
18 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAs an emerging infectious disease, the clinical and virologic course of COVID-19 requires better investigation. The aim of this study is to identify the potential risk factors associated with persistent positive nasopharyngeal swab real-time reverse transcription‒polymerase chain reaction tests in a large sample of patients who recovered from COVID-19.
methodsAfter the acute phase of SARS-CoV-2 epidemic infection, the Fondazione Policlinico A. Gemelli IRCSS of Rome established a post-acute care service for patients discharged from the hospital and recovered from COVID-19. Between April 21 and May 21, 2020, a total of 137 individuals who officially recovered from COVID-19 were enrolled in this study. All patients were tested for the SARS-CoV-2 virus with nucleic acid RT-PCR tests. Analysis was conducted in June 2020.
resultsOf the 131 patients who repeated the nasopharyngeal swab, 22 patients (16.7%) tested positive again. Some symptoms such as fatigue (51%), dyspnea (44%), and coughing (17%) were still present in a significant percentage of the patients, with no difference between patients with a negative test and those who tested positive. The likelihood of testing positive for SARS-CoV-2 infection was significantly higher among participants with persistent sore throat (prevalence ratio=6.50, 95% CI=1.38, 30.6) and symptoms of rhinitis (prevalence ratio=3.72, 95% CI=1.10, 12.5).
conclusionsThis study is the first to provide a given rate of patients (16.7%) who test positive on RT-PCR test for SARS-CoV-2 nucleic acid after recovering from COVID-19. These findings suggest that a significant proportion of patients who have recovered from COVID-19 still could be potential carriers of the virus. In particular, if patients continue to have symptoms related to COVID-19, such as sore throat and rhinitis, it is reasonable to be cautious by avoiding close contact, wearing a face mask, and possibly repeating a nasopharyngeal swab.
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