Evidence map›Paper›PMID 33040869›Full record

ReviewNeurologic clinics2020

Manganese Exposure and Neurologic Outcomes in Adult Populations.

Kaitlin V Martin, David Edmondson, Kim M Cecil, Cassandra Bezi, Miriam Leahshea Vance, Dani McBride, Erin N Haynes

Abstract readReview
In one paragraph

Review in Neurologic clinics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Severity of parkinsonism associated with environmental manganese exposure.Environmental health : a global access science source · 2021
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaitlin V MartinDepartment of Epidemiology, College of Public Health, University of Kentucky, 111 Washington Avenue Room 212C, Lexington, KY 40536, USA. Electronic address: Kaitlin.vollet.martin@uky.edu.
David EdmondsonDepartment of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Imaging Research Center, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 5033, Cincinnati, OH 45229, USA.
Kim M CecilDepartment of Radiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA; Imaging Research Center, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 5033, Cincinnati, OH 45229, USA; Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Cassandra BeziDivision of Infectious Diseases, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 7017, Cincinnati, OH 45229, USA.
Miriam Leahshea VanceDepartment of Epidemiology, College of Public Health, University of Kentucky, 111 Washington Avenue, Lexington, KY 40536, USA.
Dani McBrideDepartment of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA.
Erin N HaynesDepartment of Epidemiology, College of Public Health, University of Kentucky, 111 Washington Avenue Room 212G, Lexington, KY 40536, USA.

Funding

Pilot Project ProgramP30ES026529 · NIEHS · UNIVERSITY OF KENTUCKY · PI Erin N Haynes · 2017 to 2026
$15.4M
Developmental Effects of Manganese Exposure in Rural Adolescents: The CARES Cohort Comes of AgeR01ES026446 · NIEHS · UNIVERSITY OF KENTUCKY · PI CECIL, KIM M, HAYNES, ERIN N · 2016 to 2020
$3.1M
Marietta Community Actively Researching Exposure StudyR01ES016531 · NIEHS · UNIVERSITY OF CINCINNATI · PI HAYNES, ERIN N · 2008 to 2012
$3.0M
Internalizing Behaviors and Neuroimaging Outcomes: Impact of PBDE and PFC ExposuresR01ES027224 · NIEHS · CINCINNATI CHILDRENS HOSP MED CTR · PI CECIL, KIM M, YOLTON, KIMBERLY · 2016 to 2020
$3.0M
Retention, Maintenance and Enhancement of the Communities Actively Researching Exposure Study (CARES)R24ES030904 · NIEHS · UNIVERSITY OF KENTUCKY · PI HAYNES, ERIN N · 2020 to 2024
$1.8M
NIEHS NIH HHS P30 ES026529NIEHS NIH HHS R01 ES016531NIEHS NIH HHS R01 ES026446NIEHS NIH HHS R01 ES027224NIEHS NIH HHS R24 ES030904
6 · The paper itself

Abstract

A review of published articles examining the effects of manganese exposure to workers and community residents shows adverse neurologic outcomes. Innovative biomarkers, including those from neuroimaging, were incorporated into many of these studies to assess both manganese exposure and neurologic outcomes. A variety of health effects were evaluated, including cognitive and motor impairments. Studies of community participants residing near manganese point sources show variability in outcomes, reflecting the complexities of exposure measurement, individual absorption, and assessment of neurologic effects. The aging population provides insight into the impacts of chronic exposure in younger populations.

Indexed as

AgedHumansManganeseMiddle AgedNeurotoxicity SyndromesManganeseBrainCognitionManganeseMotor

Identifiers

PMID33040869
PMCPMC8978550

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.