Evidence map›Paper›PMID 33040772›Full record

Trial reportPublic health nutrition2021

Targeting the perinatal diet to modulate the gut microbiota increases dietary variety and prebiotic and probiotic food intakes: results from a randomised controlled trial.

Samantha L Dawson, Mohammadreza Mohebbi, Jeffrey M Craig, Phillip Dawson, Gerard Clarke, Mimi Lk Tang, Felice N Jacka

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Public health nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Samantha L DawsoniMPACT (the Institute for Mental and Physical Health and Clinical Translation), Food & Mood Centre, Deakin University, Health Education and Research Building (HERB), Level 3, PO Box 281, Geelong, VIC3220, Australia.ORCID 0000-0002-4701-1220
Mohammadreza MohebbiFaculty of Health, Biostatistics Unit, Deakin University, Geelong, Australia.
Jeffrey M CraigMurdoch Children's Research Institute, Royal Children's Hospital, Environmental & Genetic Epidemiology Research, Parkville, Australia.
Phillip DawsonCentre for Research in Assessment and Digital Learning, Deakin University, Melbourne, Australia.
Gerard ClarkeDepartment of Psychiatry and Neurobehavioural Science, University College Cork, Cork, Ireland.
Mimi Lk TangMurdoch Children's Research Institute, Royal Children's Hospital, Allergy Immunology Research, Parkville, Australia.
Felice N JackaiMPACT (the Institute for Mental and Physical Health and Clinical Translation), Food & Mood Centre, Deakin University, Health Education and Research Building (HERB), Level 3, PO Box 281, Geelong, VIC3220, Australia.
Royal Children's Hospital · AUDeakin University · AUUniversity College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the hypothesis that a perinatal educational dietary intervention focused on 'eating for the gut microbiota' improves diet quality of pregnant women pre- and postnatally.

designThe Healthy Parents, Healthy Kids study is a prospectively registered randomised controlled trial designed to evaluate the efficacy of a dietary intervention in altering the maternal and infant gut microbiota and improving perinatal diet quality. Eligible pregnant women were randomised to receive dietary advice from their healthcare provider or to additionally receive a three session dietary intervention. Dietary data were collected at gestation weeks 26, 31, 36 and postnatal week 4. Outcome measures were diet quality, dietary variety, prebiotic and probiotic food intakes, energy, fibre, saturated fat and discretionary food intakes. Between-group differential changes from baseline before and after birth in these dietary measures were assessed using generalised estimating equations.

settingMelbourne, Australia.

participantsHealthy pregnant women from gestation week 26.

resultsForty-five women were randomised (twenty-two control, twenty-three intervention). Compared with the control group, the intervention group improved diet quality prior to birth (5·66 (95 % CI 1·65, 9·67), Cohen's d: 0·82 (se 0·33)). The intervention improved dietary variety (1·05 (95 % CI 0·17, 1·94), d: 0·66 (se 0·32)) and increased intakes of prebiotic (0·8 (95 % CI 0·27, 1·33), d: 0·91 (se 0·33)) and probiotic foods (1·05 (95 % CI 0·57, 1·53), d: 1·3(se 0·35)) over the whole study period compared with the control group.

conclusionA dietary intervention focused on 'eating for the gut microbiota' can improve aspects of perinatal diet quality during and after pregnancy.

Indexed as

Gastrointestinal MicrobiomeProbioticsDietEatingFemaleHumansPrebioticsPregnancyPrebioticsBehaviour change interventionDiet qualityGut microbiotaPregnancyRandomised controlled trial

Identifiers

PMID33040772
PMCPMC10195640
OpenAlexW3091958676

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.