Evidence map›Paper›PMID 33040733›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2020

Evaluation of dyspnea of unknown etiology in HIV patients with cardiopulmonary exercise testing and cardiovascular magnetic resonance imaging.

Andrew J Patterson, Anuja Sarode, Sadeer Al-Kindi, Lauren Shaver, Rahul Thomas, Evelyn Watson, Mohamad Amer Alaiti, Yuchi Liu, Jessie Hamilton, Nicole Seiberlich and 10 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 1 country.

Andrew J PattersonHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.ORCID 0000-0002-9895-224X
Anuja SarodeKent State University, College of Public Health, Kent, OH, USA.
Sadeer Al-KindiHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Lauren ShaverHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Rahul ThomasHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Evelyn WatsonHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Mohamad Amer AlaitiHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Yuchi LiuMichigan University, Department of Biomedical Engineering, Ann Arbor, MI, USA.
Jessie HamiltonMichigan University, Department of Biomedical Engineering, Ann Arbor, MI, USA.
Nicole SeiberlichMichigan University, Department of Biomedical Engineering, Ann Arbor, MI, USA.
Imran RashidHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Robert GilkesonUniversity Hospitals Cleveland Medical Center, Department of Radiology, Cleveland, OH, USA.
Robert SchilzUniversity Hospitals Cleveland Medical Center, Department of Pulmonology, Cleveland, OH, USA.
Brian HoitHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Trevor JenkinsHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Melissa ZulloKent State University, College of Public Health, Kent, OH, USA.
Eduardo BossoneCardiology Division, Cardarelli Hospital, Naples, Italy.
Christopher LongeneckerHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA.
Orlando SimonettiOhio State University Department of Cardiovascular Medicine, Columbus, OH, USA.
Sanjay RajagopalanHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH, USA. Sanjay.Rajagopalan@UHhospitals.org.
University Hospitals of Cleveland · USUniversity of Michigan · USKent State University · USThe Ohio State University · US

Funding

EXercise MRI evaluation of HIV-PAH Longitudinal Determinants(EXHALTED)R01HL125060 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI RAJAGOPALAN, SANJAY · 2015 to 2017
$1.7M
NHLBI NIH HHS R01 HL125060
6 · The paper itself

Abstract

aimHuman Immunodeficiency Virus (HIV) patients commonly experience dyspnea for which an immediate cause may not be always apparent. In this prospective cohort study of HIV patients with exercise limitation, we use cardiopulmonary exercise testing (CPET) coupled with exercise cardiovascular magnetic resonance (CMR) to elucidate etiologies of dyspnea. METHODS AND

resultsThirty-four HIV patients on antiretroviral therapy with dyspnea and exercise limitation (49.7 years, 65% male, mean absolute CD4 count 700) underwent comprehensive evaluation with combined rest and maximal exercise treadmill CMR and CPET. The overall mean oxygen consumption (VO

conclusionWell treated patients with HIV appear to have conserved RV and LV function, contractile reserve and no evidence of exercise induced PAH. However, we found evidence of impaired ventilation suggesting a non-cardiopulmonary etiology for dyspnea.

Indexed as

Exercise TestExercise ToleranceMagnetic Resonance ImagingPulmonary VentilationAdultAnti-HIV AgentsDyspneaFemaleHIV InfectionsHumansLungMaleMiddle AgedOxygen ConsumptionPredictive Value of TestsProspective StudiesAnti-HIV AgentsContractile ReserveCPETExercise CMRHIV

Identifiers

PMID33040733
PMCPMC7549205
OpenAlexW3092296929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.