Evidence map›Paper›PMID 33040585›Full record

ArticleCirculation. Cardiovascular interventions2020

Use of Natural Language Processing to Improve Identification of Patients With Peripheral Artery Disease.

E Hope Weissler, Jikai Zhang, Steven Lippmann, Shelley Rusincovitch, Ricardo Henao, W Schuyler Jones

Abstract readComparative StudyValidation Study
In one paragraph

Article in Circulation. Cardiovascular interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  8. Unsupervised algorithms to identify potential under-coding of secondary diagnoses in hospitalisations databases in Portugal.Health information management : journal of the Health Information Management Association of Australia · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

E Hope WeisslerDivision of Vascular and Endovascular Surgery (E.H.W.), Duke University School of Medicine, Durham, NC.
Jikai ZhangDepartment of Biostatistics and Bioinformatics (J.Z., R.H.), Duke University School of Medicine, Durham, NC.
Steven LippmannDepartment of Population Health Sciences (S.L., W.S.J.), Duke University School of Medicine, Durham, NC.
Shelley RusincovitchDuke Forge (S.R., R.H.), Duke University School of Medicine, Durham, NC.
Ricardo HenaoDepartment of Biostatistics and Bioinformatics (J.Z., R.H.), Duke University School of Medicine, Durham, NC.
W Schuyler JonesDepartment of Population Health Sciences (S.L., W.S.J.), Duke University School of Medicine, Durham, NC.

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Stimulating Access to Research in Residency (StARR) - NHLBIR38HL143612 · NHLBI · DUKE UNIVERSITY · PI Mai ElMallah, David H. Harpole · 2018 to 2026
$2.6M
NCATS NIH HHS UL1 TR002553NHLBI NIH HHS R38 HL143612
6 · The paper itself

Abstract

backgroundPeripheral artery disease (PAD) is underrecognized, undertreated, and understudied: each of these endeavors requires efficient and accurate identification of patients with PAD. Currently, PAD patient identification relies on diagnosis/procedure codes or lists of patients diagnosed or treated by specific providers in specific locations and ways. The goal of this research was to leverage natural language processing to more accurately identify patients with PAD in an electronic health record system compared with a structured data-based approach.

methodsThe clinical notes from a cohort of 6861 patients in our health system whose PAD status had previously been adjudicated were used to train, test, and validate a natural language processing model using 10-fold cross-validation. The performance of this model was described using the area under the receiver operating characteristic and average precision curves; its performance was quantitatively compared with an administrative data-based least absolute shrinkage and selection operator (LASSO) approach using the DeLong test.

resultsThe median (SD) of the area under the receiver operating characteristic curve for the natural language processing model was 0.888 (0.009) versus 0.801 (0.017) for the LASSO-based approach alone (DeLong

conclusionsUsing a natural language processing approach in addition to partial cohort preprocessing with a LASSO-based model, we were able to meaningfully improve our ability to identify patients with PAD compared with an approach using structured data alone. This model has potential applications to both interventions targeted at improving patient care as well as efficient, large-scale PAD research. Graphic Abstract: A graphic abstract is available for this article.

Indexed as

Data MiningDiagnosis, Computer-AssistedNatural Language ProcessingAgedAged, 80 and overAmputation, SurgicalAnkle Brachial IndexElectronic Health RecordsEndovascular ProceduresFemaleHumansMaleMiddle AgedPeripheral Arterial DiseasePredictive Value of TestsReproducibility of Resultscohort studieselectronic health recordsmachine learningnatural language processingperipheral artery disease

Identifiers

PMID33040585
PMCPMC7577538

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.