Evidence map›Paper›PMID 33040298›Full record

ReviewPlant foods for human nutrition (Dordrecht, Netherlands)2020

Bioactive Compounds and Pharmacological Potential of Pomegranate (Punica granatum) Seeds - A Review.

Mariam Fourati, Slim Smaoui, Hajer Ben Hlima, Khaoula Elhadef, Olfa Ben Braïek, Karim Ennouri, Ahlem Chakchouk Mtibaa, Lotfi Mellouli

Abstract readReview
PubMed Publisher
In one paragraph

Review in Plant foods for human nutrition (Dordrecht, Netherlands), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pomegranate (Nutrients · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Antiangiogenic Potential of Pomegranate Extracts.Plants (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. In-Depth Chemical Characterization ofFoods (Basel, Switzerland) · 2023
    Article
  13. Review
  14. Review
  15. Review
  16. Dietary Phytochemicals that Can Extend Longevity by Regulation of Metabolism.Plant foods for human nutrition (Dordrecht, Netherlands) · 2022
    Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mariam FouratiLaboratory of Microbial, Enzymatic Biotechnology and Biomolecules (LBMEB), Center of Biotechnology of Sfax, University of Sfax-Tunisia, Road of Sidi Mansour Km 6, P. O. Box 1177, 3018, Sfax, Tunisia.
Slim SmaouiLaboratory of Microbial, Enzymatic Biotechnology and Biomolecules (LBMEB), Center of Biotechnology of Sfax, University of Sfax-Tunisia, Road of Sidi Mansour Km 6, P. O. Box 1177, 3018, Sfax, Tunisia. slim.smaoui@cbs.rnrt.tn.ORCID http://orcid.org/0000-0002-8839-7377
Hajer Ben HlimaLaboratoire de Génie Enzymatique et de Microbiologie, Equipe de Biotechnologie des Algues, Ecole Nationale d'Ingénieurs de Sfax, Université de Sfax, 3038, Sfax, Tunisia.
Khaoula ElhadefLaboratory of Microbial, Enzymatic Biotechnology and Biomolecules (LBMEB), Center of Biotechnology of Sfax, University of Sfax-Tunisia, Road of Sidi Mansour Km 6, P. O. Box 1177, 3018, Sfax, Tunisia.
Olfa Ben BraïekLaboratory of Transmissible Diseases and Biologically Active Substances (LR99ES27), Faculty of Pharmacy, University of Monastir, Monastir, Tunisia.
Karim EnnouriLaboratory of Amelioration and Protection of Olive Genetic Resources, Olive Tree Institute, Sfax University, Sfax, Tunisia.
Ahlem Chakchouk MtibaaLaboratory of Microbial, Enzymatic Biotechnology and Biomolecules (LBMEB), Center of Biotechnology of Sfax, University of Sfax-Tunisia, Road of Sidi Mansour Km 6, P. O. Box 1177, 3018, Sfax, Tunisia.
Lotfi MellouliLaboratory of Microbial, Enzymatic Biotechnology and Biomolecules (LBMEB), Center of Biotechnology of Sfax, University of Sfax-Tunisia, Road of Sidi Mansour Km 6, P. O. Box 1177, 3018, Sfax, Tunisia.
University of Sfax · TNUniversity of Monastir · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of complementary medicine has recently increased in an attempt to find effective alternative therapies that reduce the adverse effects of drugs. Pomegranate (Punica granatum L.) by-products, such as seeds, is a rich source of phytochemicals with a high antioxidant activity, thus possessing health benefits. For the identification and quantification of the pomegranate seeds chemical compounds, particular attention has been drawn to the latest developments in the HPLC coupling with electrospray ionization (ESI) MS/MS detection. In fact, a wide range of phytochemicals including phenolic acid, anthocyanins, flavonoids, hydrolysable tannins and other polyphenols were characterized. Furthermore, an exhaustive review of the scientific literature on pomegranate seeds on biomedicine and pharmacotherapy was carried out. Indeed, both in vitro and in vivo studies have demonstrated how pomegranate seeds possess antioxidant, anti- cardiovascular diseases, anti-osteoporosis, antidiabetic, anti-inflammatory and anticancer activities. The present review describes a recent tendency in research focusing on the chemical and biomedical features of the pomegranate seeds to value them as natural additives or active compounds for first-order diseases.

Indexed as

LythraceaePomegranateFruitSeedsTandem Mass SpectrometryAnalytical chemistryBioactive compoundsBiological activityHealth benefitsPomegranate seed

Identifiers

PMID33040298
OpenAlexW3092262381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.