Evidence map›Paper›PMID 33040233›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2021

Delays in surgery for cholesteatoma due to COVID-19: is there an impact on rates of recidivism and major complications?

Mohammed Hassan Hussain, Manish Mair, Sara Mahmood, Georgios Sakagiannis, Djamila M Rojoa, Firas J Raheman, Esmee Irvine, Peter Rea

Open access · bronzeAbstract read
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Modeling residual cholesteatoma growth rate: a meta-analysis of individual participant data.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. MRI-DWI detection of residual cholesteatoma: moving toward an optimum follow-up scheme.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mohammed Hassan HussainDepartment of Otolaryngology, University Hospitals of Leicester NHS Trust, 3rd Floor Balmoral Building, Infirmary Square, Leicester, LE1 5WW, UK. mohammed.hussain@doctors.org.uk.ORCID http://orcid.org/0000-0002-5988-3405
Manish MairDepartment of Otolaryngology, University Hospitals of Leicester NHS Trust, 3rd Floor Balmoral Building, Infirmary Square, Leicester, LE1 5WW, UK.
Sara MahmoodDepartment of Otolaryngology, University Hospitals of Leicester NHS Trust, 3rd Floor Balmoral Building, Infirmary Square, Leicester, LE1 5WW, UK.
Georgios SakagiannisDepartment of Otolaryngology, University Hospitals of Leicester NHS Trust, 3rd Floor Balmoral Building, Infirmary Square, Leicester, LE1 5WW, UK.
Djamila M RojoaDepartment of Otolaryngology, University Hospitals of Leicester NHS Trust, 3rd Floor Balmoral Building, Infirmary Square, Leicester, LE1 5WW, UK.
Firas J RahemanDepartment of Otolaryngology, University Hospitals of Leicester NHS Trust, 3rd Floor Balmoral Building, Infirmary Square, Leicester, LE1 5WW, UK.
Esmee IrvineDepartment of Otolaryngology, University Hospitals of Leicester NHS Trust, 3rd Floor Balmoral Building, Infirmary Square, Leicester, LE1 5WW, UK.
Peter ReaDepartment of Otolaryngology, University Hospitals of Leicester NHS Trust, 3rd Floor Balmoral Building, Infirmary Square, Leicester, LE1 5WW, UK.
University Hospitals of Leicester NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the relationship between the waiting time for surgery, and cholesteatoma recidivism rates and major complications. The secondary aims were to identify any other prognostic factors for cholesteatoma recidivism.

methodsA retrospective single-centre study of 312 patients who underwent cholesteatoma surgery under the care of a single-surgeon, between 2004 and 2018, was performed. Waiting times for surgery were categorised into ≤ 90 days, 91-180 days, 181-270 days and > 271 days. The outcome measures were cholesteatoma recidivism and major complications (facial nerve palsy or intracranial complications).

resultsThe mean age was 36.1 years ± 21.5 with 242 adults (77.6%) and 70 children (22.4%). The mean waiting time for surgery was 126.2 days (4.1 months) ± 96.0 days and the overall rate of recidivism was 11.2% (35/312 patients). No instances of facial nerve palsy or intracranial complications were identified. Rates of recidivism by waiting time for surgery were: 15.3% for 118 patients who waited ≤ 90 days, 9.7% for 134 patients who waited 91-180 days, 6.7% for 30 patients who waited 181-270 days and 4.3% for 23 patients who waited > 271 days. There was no significant difference amongst the different waiting time groups for rates of recidivism (p = 0.266).

conclusionIncreased waiting times for cholesteatoma surgery do not appear to be associated with increased rates of recidivism or major complications. Clinical judgement will always be required for complicated disease or patients with additional risk factors. The other prognostic factors for recidivism identified in this study were age (< 15 years) and congenital cholesteatoma.

Indexed as

Cholesteatoma, Middle EarCOVID-19RecidivismAdolescentAdultChildHumansMastoidRetrospective StudiesSARS-CoV-2Treatment OutcomeCholesteatomaMastoidRecidivismRecurrenceTime factors

Identifiers

PMID33040233
PMCPMC7547560
OpenAlexW3092228039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.