Evidence map›Paper›PMID 33040025›Full record

ArticleThe Journal of biological chemistry2020

Carnosine synthase deficiency is compatible with normal skeletal muscle and olfactory function but causes reduced olfactory sensitivity in aging mice.

Lihua Wang-Eckhardt, Asisa Bastian, Tobias Bruegmann, Philipp Sasse, Matthias Eckhardt

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lihua Wang-EckhardtInstitute of Biochemistry and Molecular Biology, University of Bonn, Bonn, Germany.
Asisa BastianInstitute of Biochemistry and Molecular Biology, University of Bonn, Bonn, Germany.
Tobias BruegmannInstitute of Physiology I, Medical Faculty, University of Bonn, Bonn, Germany.
Philipp SasseInstitute of Physiology I, Medical Faculty, University of Bonn, Bonn, Germany.
Matthias EckhardtInstitute of Biochemistry and Molecular Biology, University of Bonn, Bonn, Germany. Electronic address: eckhardt@uni-bonn.de.
University of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carnosine (β-alanyl-l-histidine) and anserine (β-alanyl-3-methyl-l-histidine) are abundant peptides in the nervous system and skeletal muscle of many vertebrates. Many

Indexed as

Muscle ContractionAgingAnimalsCarnosineMiceMice, KnockoutMuscle, SkeletalPeptide SynthasesReceptors, OdorantCarnosinecarnosine synthetasePeptide SynthasesReceptors, Odorantaginganserinecarnosinehistidine-containing dipeptide (HSD)neurochemistryneuropeptideneuroscienceolfactionolfactory epithelium (OE)olfactory receptor neuron (ORN)peptides

Identifiers

PMID33040025
PMCPMC7863879
OpenAlexW3092306702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.