Evidence map›Paper›PMID 33039776›Full record

ArticleJournal of affective disorders2021

Identifying risk factors and detection strategies for adolescent depression in diverse global settings: A Delphi consensus study.

Syed Shabab Wahid, Katherine Ottman, Raya Hudhud, Kamal Gautam, Helen L Fisher, Christian Kieling, Valeria Mondelli, Brandon A Kohrt

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in Journal of affective disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 70 citations in OpenAlex.

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  20. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Syed Shabab WahidDivision of Global Mental Health, George Washington University, Washington DC, United States. Electronic address: sswahid@gwu.edu.
Katherine OttmanDivision of Global Mental Health, George Washington University, Washington DC, United States. Electronic address: keottman@gwu.edu.
Raya HudhudDepartment of Environmental and Occupational Health, George Washington University, Washington DC, United States. Electronic address: hudhudr@gwmail.gwu.edu.
Kamal GautamTranscultural Psychosocial Organization Nepal (TPO Nepal), Baluwatar, Kathmandu, Nepal. Electronic address: drkamal.gautam@gmail.com.
Helen L FisherSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, and ESRC Centre for Society and Mental Health, King's College London, London, United Kingdom. Electronic address: helen.2.fisher@kcl.ac.uk.
Christian KielingDepartment of Psychiatry, Universidade Federal do Rio Grande do Sul; and Child & Adolescent Psychiatry Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil. Electronic address: ckieling@ufrgs.br.
Valeria MondelliDepartment of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom. Electronic address: valeria.mondelli@kcl.ac.uk.
Brandon A KohrtDivision of Global Mental Health, George Washington University, Washington DC, United States. Electronic address: bkohrt@gwu.edu.
George Washington University · USKing's College London · GBGeorge Washington University Hospital · USNLR Nepal · NPUniversidade Federal do Rio Grande do Sul · BR

Funding

Reducing Barriers to Mental Health Task SharingK01MH104310 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI KOHRT, BRANDON ALAN · 2014 to 2018
$908k
Medical Research Council MC_PC_MR/R019460/1NIMH NIH HHS K01 MH104310
6 · The paper itself

Abstract

backgroundAdolescence represents a vulnerable period for the onset of depression. Globally, there is a need to better understand risk factors for adolescent depression to inform policies for effective prevention initiatives.

methodsA Delphi consensus study was conducted on risk factors, early signs, and detection strategies for adolescent depression in global settings. Over 3 survey rounds, global experts formulated and ranked these variables for (1) specificity for adolescent depression and (2) feasibility of measurement (round 1, n=21 participants; rounds 2 and 3, n=17). We calculated Smith's salience index as a measure of consensus. Interviews were conducted with 10 participants to elicit qualitative reflections on the ranking results, and on the influence of cultural and contextual factors on depression risks.

resultsThirty-one risk factors for adolescent depression were generated. Panelists ranked three as highly specific and highly feasible to measure: family history of depression, exposure to bullying, and a negative family environment. Six were ranked as modestly specific and highly feasible: physical illness or disability, female sex, bereavement, trauma exposure, substance abuse, and low self-esteem. An additional 5 items were modestly specific and modestly feasible: social difficulties, academic stress, poverty, loss of family, and cognitive distortions. Five symptoms were at least modestly specific and feasible to measure: mood changes, loss of interest, social isolation, suicidality, and sleep changes. Schools were considered the most feasible place for screening. LIMITATIONS: The participants were not representative of all countries and cultural regions.

conclusionsThis study offers a profile of risk factors developed and prioritized by experts to inform a research agenda for risk, identification and prevention of adolescent depression across global settings.

Indexed as

DepressionSocial IsolationAdolescentDelphi TechniqueFemaleHumansRisk FactorsSurveys and QuestionnairesadolescentDelphidepressiondetectionpreventionrisk

Identifiers

PMID33039776
PMCPMC7758738
OpenAlexW3090748091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.