Evidence map›Paper›PMID 33039726›Full record

ArticleCancer epidemiology2020

Dietary glycemic index, glycemic load, and lung cancer risk: A case-control study in Los Angeles County.

Chun-Pin Chang, Travis J Meyers, Alan Fu, Ming-Yan Zhang, Donald P Tashkin, Jian-Yu Rao, Wendy Cozen, Thomas M Mack, Mia Hashibe, Hal Morgenstern and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chun-Pin ChangDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, United States; Division of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, Huntsman Cancer Institute, Salt Lake City, UT, United States.
Travis J MeyersDepartment of Epidemiology and Biostatistics, University of California, San Francisco (UCSF), San Francisco, CA, United States.
Alan FuDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, United States.
Ming-Yan ZhangDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, United States.
Donald P TashkinDivision of Pulmonary and Critical Care Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
Jian-Yu RaoDepartment of Pathology, Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, United States.
Wendy CozenDepartments of Preventive Medicine and Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Thomas M MackDepartments of Preventive Medicine and Pathology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Mia HashibeDivision of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, Huntsman Cancer Institute, Salt Lake City, UT, United States.
Hal MorgensternDepartments of Epidemiology and Environmental Health Sciences, School of Public Health and Department of Urology, Medical School, University of Michigan, Ann Arbor, MI, United States.
Zuo-Feng ZhangDepartment of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, United States. Electronic address: zfzhang@ucla.edu.

Funding

UCLA SPORE IN LUNG CANCERP50CA090388 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2001 to 2008
$13.0M
UCLA CANCER EPIDEMIOLOGY TRAINING PROGRAMT32CA009142 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 1986 to 2024
$6.3M
LUNG CANCER CHEMOPREVENTION WITH CELECOXIB IN EX-SMOKERSU01CA096134 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAO, JENNY T · 2002 to 2007
$5.1M
Stem Cell Selection &Expansion Via HOX Gene ActivationR01CA090833 · NCI · UNIVERSITY OF PENNSYLVANIA · PI EMERSON, STEPHEN G · 2001 to 2010
$2.6M
MARIJUANA USE AND THE RISKS OF LUNG AND OTHER CANCERSR01DA011386 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MORGENSTERN, HAL M · 1999 to 2003
$1.8M
Molecular Epidemiology and Gene-Environment InteractionR21ES011667 · NIEHS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 2002 to 2004
$651k
HELICOBACTER PYLORI MALNUTRITION AND GASTRIC CANCERR03CA077954 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHANG, ZUO-FENG · 1997 to 1998
–
NCI NIH HHS P50 CA090388NCI NIH HHS R01 CA090833NCI NIH HHS R03 CA077954NCI NIH HHS T32 CA009142NCI NIH HHS U01 CA096134NIDA NIH HHS R01 DA011386NIEHS NIH HHS R21 ES011667
6 · The paper itself

Abstract

backgroundAlthough there is some evidence of positive associations between both the glycemic index (GI) and glycemic load (GL) with cancer risk, the relationships with lung cancer risk remain largely unexplored. We evaluated the associations between GI and GL with lung cancer.

methodsThe analyses were performed using data from a population-based case-control study recruited between 1999 and 2004 in Los Angeles County. Dietary factors were collected from 593 incident lung cancer cases and 1026 controls using a modified food frequency questionnaire. GI and GL were estimated using a food composition table. Adjusted odds ratios (ORs) and 95 % confidence intervals (CI) were estimated using unconditional logistic regression adjusting for potential confounders.

resultsDietary GI was positively associated with lung cancer (OR for upper vs. lower tertile = 1.62; 95 % CI: 1.17, 2.25). For histologic subtypes, positive associations were observed between GI and adenocarcinoma (OR for upper vs. lower tertile = 1.82; 95 % CI: 1.22, 2.70) and small cell carcinoma (OR for upper vs. lower tertile = 2.68; 95 % CI: 1.25, 5.74). No clear association between GL and lung cancer was observed.

conclusionThese findings suggest that high dietary GI was associated with increased lung cancer risk, and the positive associations were observed for both lung adenocarcinoma and small cell lung carcinoma. Replication in an independent dataset is merited for a broader interpretation of our results.

Indexed as

AdolescentAdultAgedCase-Control StudiesFemaleGlycemic IndexGlycemic LoadHumansLos AngelesLung NeoplasmsMaleMiddle AgedRisk FactorsYoung AdultEpidemiologyGlycemic indexGlycemic loadLung adenocarcinomaLung cancerRisk factorSmall cell lung carcinoma

Identifiers

PMID33039726
PMCPMC7734880

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.