Evidence map›Paper›PMID 33039144›Full record

ArticleTransplantation proceedings2020

Recovery of Moderate Coronavirus Disease 2019 in a Liver Transplant Recipient on Continued Immunosuppression: A Case Report.

Victor Dahl Mathiasen, Stine Karlsen Oversoe, Peter Ott, Søren Jensen-Fangel, Steffen Leth

Abstract readCase Reports
In one paragraph

Article in Transplantation proceedings, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. COVID-19 Minisymposium: Toward a Strategic Roadmap.Transplantation proceedings · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Victor Dahl MathiasenDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark. Electronic address: victordahl@gmail.com.
Stine Karlsen OversoeDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Peter OttDepartment of Hepatology and Gastroenterology, Aarhus University Hospital, Aarhus, Denmark.
Søren Jensen-FangelDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.
Steffen LethDepartment of Infectious Diseases, Aarhus University Hospital, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has had an enormous impact on the world. Owing to limited data available, it remains unclear to what extent liver transplant recipients should be considered at a higher risk of severe disease. We describe a moderate course of coronavirus disease 2019 (COVID-19) in a patient who underwent a liver transplant 2 years earlier because of Budd-Chiari syndrome. The patient presented with malaise, headache, dry cough, and fever for 4 days. Immunosuppressive therapy with tacrolimus and mycophenolate mofetil was continued throughout the course of infection. Oxygen therapy was given for a single night, and the patient gradually recovered with supportive care only. With this case report, we demonstrate that liver transplantation and immunosuppression is not necessarily associated with severe COVID-19 and emphasize that more information on this matter is urgently required. Withdrawal of immunosuppressive therapy could be associated with higher mortality.

Indexed as

Immunocompromised HostLiver TransplantationBetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansImmunosuppressive AgentsMiddle AgedPandemicsPneumonia, ViralSARS-CoV-2Immunosuppressive Agents

Identifiers

PMID33039144
PMCPMC7498236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.