Evidence map›Paper›PMID 33039030›Full record

ReviewPlacenta2020

Fat-soluble nutrients and Omega-3 fatty acids as modifiable factors influencing preterm birth risk.

Melissa Thoene, Matthew Van Ormer, Ana Yuil-Valdes, Taylor Bruett, Sathish Kumar Natarajan, Maheswari Mukherjee, Maranda Thompson, Tara M Nordgren, Wendy Van Lippevelde, Nina C Overby and 3 more

Open access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Placenta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Melissa ThoeneDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, 68198, USA. Electronic address: melissak.thoene@unmc.edu.
Matthew Van OrmerDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, 68198, USA. Electronic address: matthew.vanormer@unmc.edu.
Ana Yuil-ValdesDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, 68198, USA. Electronic address: ana.yuilvaldes@unmc.edu.
Taylor BruettDepartment of Nutrition & Health Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68583, USA. Electronic address: tbruett2@unl.edu.
Sathish Kumar NatarajanDepartment of Nutrition & Health Sciences, University of Nebraska-Lincoln, Lincoln, NE, 68583, USA. Electronic address: snatarajan2@unl.edu.
Maheswari MukherjeeCytotechnology Education, College of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE, 68198, USA. Electronic address: mmukherj@unmc.edu.
Maranda ThompsonDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, 68198, USA. Electronic address: maranda.thompson@unmc.edu.
Tara M NordgrenDivision of Biomedical Sciences, School of Medicine, University of California, Riverside, Riverside, CA, 92521, USA. Electronic address: tmnordgren@gmail.com.
Wendy Van LippeveldeDepartment of Nutrition and Public Health, University of Agder, Post-box 422, N-4604, Kristiansand, Norway; Department of Marketing, Innovation and Organization, Ghent University, Ghent, Belgium. Electronic address: wendy.vanlippevelde@ugent.be.
Nina C OverbyDepartment of Nutrition and Public Health, University of Agder, Post-box 422, N-4604, Kristiansand, Norway. Electronic address: nina.c.overby@uia.no.
Kwame Adu-BonsaffohUniversity of Ghana Medical School, Department of Obstetrics and Gynecology, P.O. Box GP 4236, Accra, Ghana. Electronic address: bonsaffoh@yahoo.com.
Ann Anderson-BerryDepartment of Pediatrics, University of Nebraska Medical Center, Omaha, NE, 68198, USA. Electronic address: alanders@unmc.edu.
Corrine HansonMedical Nutrition Education, College of Allied Health Professions, University of Nebraska Medical Center Omaha, NE, 68198, USA. Electronic address: ckhanson@unmc.edu.
Nebraska Medical Center · USUniversity of Agder · NOUniversity of Nebraska–Lincoln · USUniversity of California, Riverside · USUniversity of Ghana · GH

Funding

The role of stress in the fetal origin of obesity and metabolic dysfunctionP20GM104320 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI ZEMPLENI, JANOS · 2014 to 2024
$24.9M
The Environmental Assessments Core (FSC)P50MD010431 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2015 to 2019
$3.5M
The role of omega-3 fatty acids and bioactive lipid signaling in airway inflammation and resolution following organic dust exposuresR00ES025819 · NIEHS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI NORDGREN, TARA M · 2017 to 2019
$747k
NIEHS NIH HHS R00 ES025819NIGMS NIH HHS P20 GM104320NIMHD NIH HHS P50 MD010431
6 · The paper itself

Abstract

Preterm birth is a leading cause of child morbidity and mortality, so strategies to reduce early birth must remain a priority. One key approach to enhancing birth outcomes is improving maternal dietary intake. Therefore, the purpose of this review is to discuss mechanisms on perinatal status of fat-soluble nutrients (carotenoids, retinol, tocopherols) and omega-3 fatty acids and how they impact risk for preterm birth. Literature review demonstrates that maternal dietary intake and biological (blood and placental tissue) levels of fat-soluble nutrients during pregnancy may provide antioxidative, anti-inflammatory, and immunomodulatory health benefits. Omega-3 fatty acids also promote increased production of specialized pro-resolving mediators, subsequently mediating inflammation resolution. Combined effects of these nutrients support appropriate placental organogenesis and function. Consequently, fat-soluble nutrients and omega-3 fatty acids serve as strong influencers for preterm birth risk. As dietary intake remains a modifiable factor, future intervention would benefit from a focus on optimizing perinatal status of these specific nutrients.

Indexed as

Dietary SupplementsFatty Acids, Omega-3FemaleHumansPhytochemicalsPregnancyPremature BirthFatty Acids, Omega-3PhytochemicalsCarotenoidOmega-3PlacentaPreterm birthRetinolTocopherol

Identifiers

PMID33039030
PMCPMC7548396
OpenAlexW2994045127

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.