ArticleAngewandte Chemie (International ed. in English)2021
Arynes as Radical Acceptors: TEMPO-Mediated Cascades Comprising Addition, Cyclization, and Trapping.
Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- How Alkali Metal Alkoxides Initiate Organic Radical Reactions.Journal of the American Chemical Society · 2026Article
- Reaction of Blatter and Verdazyl Radicals with Arynes: Synthesis and Investigation of N-Chiral, Antiaromatic Triazines, and Tetrazinones.Angewandte Chemie (International ed. in English) · 2026Article
- Intermolecular radical oxyalkylation of arynes with alkenes and TEMPO.Chemical science · 2024Article
- Stereoselective Alder-Ene Reactions of Bicyclo[1.1.0]butanes: Facile Synthesis of Cyclopropyl- and Aryl-Substituted Cyclobutenes.Journal of the American Chemical Society · 2024Article
- Novel transition metal-free synthetic protocols toward the construction of 2,3-dihydrobenzofurans: a recent update.Frontiers in chemistry · 2024Review
- Aryne-Enabled C-N Arylation of Anilines.Angewandte Chemie (International ed. in English) · 2023Article
- Empowering boronic acids as hydroxyl synthons for aryne induced three-component coupling reactions.Chemical science · 2023Article
- Difunctionalization of Dienes, Enynes and Related Compounds via Sequential Radical Addition and Cyclization Reactions.Molecules (Basel, Switzerland) · 2023Review
- Photoredox catalysis harvesting multiple photon or electrochemical energies.Beilstein journal of organic chemistry · 2023Review
- Article
- Interception of 1,2-cyclohexadiene with TEMPO radical.Tetrahedron letters · 2021Article
- Synthetic exploration of sulfinyl radicals using sulfinyl sulfones.Nature communications · 2021Article
- Chemoselective γ-Oxidation of β,γ-Unsaturated Amides with TEMPO.Angewandte Chemie (International ed. in English) · 2021Article
- Chemoselektive γ-Oxidation von β,γ-ungesättigten Amiden mit TEMPO.Angewandte Chemie (Weinheim an der Bergstrasse, Germany) · 2021Article
- Arynes as Radical Acceptors: TEMPO-Mediated Cascades Comprising Addition, Cyclization, and Trapping.Angewandte Chemie (International ed. in English) · 2021Article
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3 authors.
Funding
Abstract
The application of arynes as radical acceptors is described. The stable radical TEMPO (2,2,6,6-tetramethyl piperidine 1-oxyl) is shown to add to various ortho-substituted benzynes generating the corresponding aryl radicals which engage in 5-exo or 6-endo cyclizations. The cyclized radicals are eventually trapped by TEMPO. The introduced method provides ready access to various dihydrobenzofurans, oxindoles, and sultones by a conceptually novel approach.
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