Evidence map›Paper›PMID 33038007›Full record

Trial reportInternational journal of cosmetic science2020

Topical niacinamide enhances hydrophobicity and resilience of corneocyte envelopes on different facial locations.

R Voegeli, D Guneri, M Cherel, B Summers, M E Lane, A V Rawlings

Open access · hybridAbstract readLetterRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of cosmetic science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 5 countries.

R VoegeliDSM Nutritional Products Ltd, Wurmisweg 576, 4303 Kaiseraugst, Switzerland.ORCID https://orcid.org/0000-0002-3951-0329
D GuneriUCL School of Pharmacy, 29-39 Brunswick Square, WC1N 1AX, London, UK.ORCID https://orcid.org/0000-0003-0858-1746
M CherelNewtone Technologies, 13bis, place Jule Ferry, 69006, Lyon, France.
B SummersSefako Makgatho Health Sciences University, Basic Medical Sciences Building, Room N311, 3rd Floor, Molotlegi St., Medunsa 0204, Pretoria, Gauteng, South Africa.
M E LaneUCL School of Pharmacy, 29-39 Brunswick Square, WC1N 1AX, London, UK.ORCID https://orcid.org/0000-0002-7904-3614
A V RawlingsUCL School of Pharmacy, 29-39 Brunswick Square, WC1N 1AX, London, UK.ORCID https://orcid.org/0000-0003-4740-6502
Medway School of Pharmacy · GBDSM (Netherlands) · NLSefako Makgatho Health Sciences University · ZAThermo Fisher Scientific (Norway) · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related differences in maturation parameters of corneocyte envelopes (size, hydrophobicity and rigidity) were examined at several facial test sites in young and old female Caucasians. In addition, the effect of topically applied niacinamide on these parameters was evaluated in a 4-week placebo-controlled study.

Indexed as

FaceAdministration, TopicalAdultFemaleHumansHydrophobic and Hydrophilic InteractionsMiddle AgedNiacinamidePlacebosSkinNiacinamidePlacebos

Identifiers

PMID33038007
PMCPMC8365309
OpenAlexW3092570037

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.