Evidence map›Paper›PMID 33037910›Full record

ArticleEuropean radiology2021

The value of re-staging chest CT at first local recurrence of extremity and trunk soft tissue sarcoma.

Mirza S Baig, Wais Habib, Veronica Attard, Ban Sharif, Daniel Lindsay, Bhavin Upadhyay, Asif Saifuddin

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Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. [Preoperative diagnostics and typing of abdominal soft tissue sarcomas].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Mirza S BaigQueen Elizabeth Hospital Critical Care, Lewisham and Greenwich NHS Trust, Stadium Road, Woolwich, London, SE18 4QH, UK. mirza.baig7@nhs.net.ORCID http://orcid.org/0000-0001-8592-6838
Wais HabibBarts and the London School of Medicine and Dentistry, Garrod Building, Turner St, Whitechapel, London, E1 2AD, UK.
Veronica AttardDepartment of Medical Imaging, Mater Dei Hospital, Triq Dun Karm, L-Imsida, MSD2090, Malta.
Ban SharifRadiology Department, Northwick Park Hospital, Watford Road, Harrow, HA1 3UJ, UK.
Daniel LindsayDepartment of Histopathology, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, UK.
Bhavin UpadhyayDepartment of Imaging, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, UK.
Asif SaifuddinDepartment of Imaging, Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, HA7 4LP, UK.
Royal National Orthopaedic Hospital · GBMater Dei Hospital · MTNorthwick Park Hospital · GBQueen Elizabeth Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the prevalence of pulmonary metastases on re-staging chest CT at the time of first local recurrence (LR) of trunk or extremity soft tissue sarcoma (STS). MATERIALS AND

methodsRetrospective review of all patients diagnosed with recurrent STS between May 2007 and April 2018. Data collected included patient age and sex, site of primary STS, time to LR, recurrence site, initial tumour grade, recurrent tumour grade, findings of initial staging chest CT, and prevalence of pulmonary metastases on re-staging chest CT.

resultsThe study included 109 patients (males = 68, females = 41; mean age 56 years, range 9-92 years). The commonest tumour sub-types were myxofibrosarcoma (27.5%), undifferentiated pleomorphic/spindle cell sarcoma (20.2%), synovial sarcoma (10.1%), and malignant peripheral nerve sheath tumour (10.1%). Initial staging chest CT demonstrated pulmonary metastases in 1 of 77 (1.3%) patients for whom CT was available for review. The mean time to LR was 30.8 months (range 3-224 months). Pulmonary metastases were diagnosed on re-staging chest CT in 26 of 109 cases (23.9%), being commonest with grade 3 STS (36.1%). Pleomorphic sarcoma (85.7%) and undifferentiated spindle cell sarcoma (33.3%) were the 2 commonest tumour sub-types associated with pulmonary metastases at first LR.

conclusionRe-staging chest CT at the time of first LR of STS identified a prevalence of 23.9% pulmonary metastases, which supports the need for chest CT at the time of LR in line with the UK guidelines for the management of bone and soft tissue sarcoma. KEY POINTS: • Pulmonary metastases were diagnosed in 1.3% of soft tissue sarcomas at presentation. • Pulmonary metastases were identified in ~ 24% of patients at first local recurrence of soft tissue sarcoma, most commonly with pleomorphic sarcoma and Trojani grade tumours. • No patient with a low-grade recurrence had pulmonary metastases.

Indexed as

SarcomaSoft Tissue NeoplasmsAdolescentAdultAgedAged, 80 and overChildExtremitiesFemaleHumansMaleMiddle AgedNeoplasm Recurrence, LocalRetrospective StudiesTomography, X-Ray ComputedYoung AdultNeoplasm metastasisNeoplasm Recurrence, LocalSarcomaTomography, X-ray computed

Identifiers

PMID33037910
OpenAlexW3092276066

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.