ArticleCerebral cortex (New York, N.Y. : 1991)2021
Brain Connectivity, and Hormonal and Behavioral Correlates of Sustained Weight Loss in Obese Patients after Laparoscopic Sleeve Gastrectomy.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 29 citations in OpenAlex.
- Large-Scale Brain Network Connectivity Mediates the Association Between Metabolic Risk Factors and Cognition: An fMRI Study of the Human Connectome Project.International journal of endocrinology and metabolism · 2026Article
- Harnessing food cue evoked neuroimaging towards treatment optimisation for obesity and binge eating disorder.Reviews in endocrine & metabolic disorders · 2026Review
- The Interplay Between Psychological and Neurobiological Predictors of Weight Regain: A Narrative Review.Nutrients · 2025Review
- Medial orbitofrontal cortex structure, function, and cognition associates with weight loss for laparoscopic sleeve gastrectomy.Obesity (Silver Spring, Md.) · 2025Article
- Short-Term Outcomes of Laparoscopic Sleeve Gastrectomy for Weight Loss and Gastroesophageal Reflux Disease.Cureus · 2025Article
- FTO variant is associated with changes in BMI, ghrelin, and brain function following bariatric surgery.JCI insight · 2024Article
- Body mass index-dependent shifts along large-scale gradients in human cortical organization explain dietary regulatory success.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Obesity is associated with alterations in anatomical connectivity of frontal-corpus callosum.Cerebral cortex (New York, N.Y. : 1991) · 2024Article
- Sustained improvements in brain health and metabolic markers 24 months following bariatric surgery.Brain communications · 2024Article
- Novel Insights into the Physiology of Nutrient Sensing and Gut-Brain Communication in Surgical and Experimental Obesity Therapy.Obesity surgery · 2023Review
- Associations among body mass index, working memory performance, gray matter volume, and brain activation in healthy children.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions.Molecular psychiatry · 2023Review
- Habenular connectivity predict weight loss and negative emotional-related eating behavior after laparoscopic sleeve gastrectomy.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Regulation of body weight: Lessons learned from bariatric surgery.Molecular metabolism · 2023Review
- Neuroimaging and neuroendocrine insights into food cravings and appetite interventions in obesity.Psychoradiology · 2023Review
- Intermittent energy restriction changes the regional homogeneity of the obese human brain.Frontiers in neuroscience · 2023Article
- Dynamical alterations of brain function and gut microbiome in weight loss.Frontiers in cellular and infection microbiology · 2023Article
- Gut-brain mechanisms underlying changes in disordered eating behaviour after bariatric surgery: a review.Reviews in endocrine & metabolic disorders · 2022Review
- Computational approaches to predicting treatment response to obesity using neuroimaging.Reviews in endocrine & metabolic disorders · 2022Review
- Alterations in Functional and Structural Connectivity of Basal Ganglia Network in Patients with Obesity.Brain topography · 2022Article
Corrections and comments
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Authors and funding
19 authors at 6 institutions in 2 countries.
Funding
Abstract
The biological mediators that support cognitive-control and long-term weight-loss after laparoscopic sleeve gastrectomy (LSG) remain unclear. We measured peripheral appetitive hormones and brain functional-connectivity (FC) using magnetic-resonance-imaging with food cue-reactivity task in 25 obese participants at pre, 1 month, and 6 month after LSG, and compared with 30 normal weight controls. We also used diffusion-tensor-imaging to explore whether LSG increases brain structural-connectivity (SC) of regions involved in food cue-reactivity. LSG significantly decreased BMI, craving for high-calorie food cues, ghrelin, insulin, and leptin levels, and increased self-reported cognitive-control of eating behavior. LSG increased FC between the right dorsolateral prefrontal cortex (DLPFC) and the pregenual anterior cingulate cortex (pgACC) and increased SC between DLPFC and ACC at 1 month and 6 month after LSG. Reduction in BMI correlated negatively with increased FC of right DLPFC-pgACC at 1 month and with increased SC of DLPFC-ACC at 1 month and 6 month after LSG. Reduction in craving for high-calorie food cues correlated negatively with increased FC of DLPFC-pgACC at 6 month after LSG. Additionally, SC of DLPFC-ACC mediated the relationship between lower ghrelin levels and greater cognitive control. These findings provide evidence that LSG improved functional and structural connectivity in prefrontal regions, which contribute to enhanced cognitive-control and sustained weight-loss following surgery.
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