Evidence map›Paper›PMID 33037740›Full record

ArticleGlobal change biology2021

Warming temperatures could expose more than 1.3 billion new people to Zika virus risk by 2050.

Sadie J Ryan, Colin J Carlson, Blanka Tesla, Matthew H Bonds, Calistus N Ngonghala, Erin A Mordecai, Leah R Johnson, Courtney C Murdock

Abstract read
In one paragraph

Article in Global change biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  6. The Effect of Increased Temperature on Dengue Virus in the VectorTropical medicine and infectious disease · 2026
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sadie J RyanDepartment of Geography, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0002-4308-6321
Colin J CarlsonDepartment of Biology, Georgetown University, Washington, DC, USA.ORCID https://orcid.org/0000-0001-6960-8434
Blanka TeslaDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
Matthew H BondsDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Calistus N NgonghalaEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0002-8441-9495
Erin A MordecaiBiology Department, Stanford University, Stanford, CA, USA.
Leah R JohnsonDepartment of Statistics, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.ORCID https://orcid.org/0000-0002-9922-579X
Courtney C MurdockDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.

Funding

Leveraging environmental drivers to predict vector-borne disease transmissionR35GM133439 · NIGMS · STANFORD UNIVERSITY · PI Erin Mordecai · 2019 to 2026
$3.2M
Division of Environmental Biology NSF DEB-1518681Division of Environmental Biology NSF-RAPID 1640780Helman ScholarshipNIGMS NIH HHS 1R35GM133439-01NIGMS NIH HHS R35 GM133439Stanford University King Center for Global Development Seed GrantTerman Award
6 · The paper itself

Abstract

In the aftermath of the 2015 pandemic of Zika virus (ZIKV), concerns over links between climate change and emerging arboviruses have become more pressing. Given the potential that much of the world might remain at risk from the virus, we used a previously established temperature-dependent transmission model for ZIKV to project climate change impacts on transmission suitability risk by mid-century (a generation into the future). Based on these model predictions, in the worst-case scenario, over 1.3 billion new people could face suitable transmission temperatures for ZIKV by 2050. The next generation will face substantially increased ZIKV transmission temperature suitability in North America and Europe, where naïve populations might be particularly vulnerable. Mitigating climate change even to moderate emissions scenarios could significantly reduce global expansion of climates suitable for ZIKV transmission, potentially protecting around 200 million people. Given these suitability risk projections, we suggest an increased priority on research establishing the immune history of vulnerable populations, modeling when and where the next ZIKV outbreak might occur, evaluating the efficacy of conventional and novel intervention measures, and increasing surveillance efforts to prevent further expansion of ZIKV.

Indexed as

AedesZika VirusZika Virus InfectionAnimalsEuropeHumansMosquito VectorsNorth AmericaTemperatureAedes aegyptiarbovirusesclimate changedisease riskvector-borne diseasesZika virus

Identifiers

PMID33037740
PMCPMC7756632

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.