Evidence map›Paper›PMID 33037632›Full record

Trial reportJournal of the American Geriatrics Society2021

Effect of a Multifactorial Fall Injury Prevention Intervention on Patient Well-Being: The STRIDE Study.

Thomas M Gill, Shalender Bhasin, David B Reuben, Nancy K Latham, Katy Araujo, David A Ganz, Chad Boult, Albert W Wu, Jay Magaziner, Neil Alexander and 36 more

Registry-linked trialAbstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05245097 (Mitigation of Major Hip Injury Due to Fall in an At-Risk, Older Adult Population With a Wearable Smart Belt), which is not on this map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05245097 nacompletednot on this mapstarted 2022, after this paper: background citation

Mitigation of Major Hip Injury Due to Fall in an At-Risk, Older Adult Population With a Wearable Smart Belt

TypeinterventionalSponsorActiveProtective Technologies, IncRan2022 to 2023Enrolled471ConditionsHip Injuries, Fractures, Hip, Fall Injury, Fall RiskArmsTango Belt, Standard of Care (SOC)
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Validation of a Rule-Based ICD-10-CM Algorithm to Detect Fall Injuries in Medicare Data.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Potential Solutions for the Mitigation of Hip Injuries Caused by Falls in Older Adults: A Narrative Review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Review
  11. Observational
  12. Real World Evidence of Wearable Smartbelt for Mitigation of Fall Impact in Older Adult Care.IEEE journal of translational engineering in health and medicine · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors.

Thomas M Gill *Yale Claude D. Pepper Older Americans Independence Center, Yale University, New Haven, Connecticut, USA.ORCID 0000-0002-6450-0368
Shalender Bhasin *Boston Claude D. Pepper Older Americans Independence Center, Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts, USA.
David B Reuben *Multicampus Program in Geriatric Medicine and Gerontology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Nancy K LathamBoston Claude D. Pepper Older Americans Independence Center, Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Katy AraujoYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.
David A GanzMulticampus Program in Geriatric Medicine and Gerontology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Chad BoultJohns Hopkins University, Baltimore, Maryland, USA.
Albert W WuJohns Hopkins University, Baltimore, Maryland, USA.
Jay MagazinerUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Neil AlexanderUniversity of Michigan, Ann Arbor, Michigan, USA.
Robert B WallaceUniversity of Iowa, Iowa City, Iowa, USA.
Michael E MillerSchool of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
Thomas G TravisonBoston Claude D. Pepper Older Americans Independence Center, Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Susan L GreenspanPittsburgh Claude D. Pepper Older Americans Independence Center, Division of Geriatrics and Gerontology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jerry H GurwitzMeyers Primary Care Institute, A Joint Endeavor of Reliant Medical Group, Fallon Health and University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Jeremy RichHealthCare Partners, El Segundo, California, USA.
Elena VolpiUniversity of Texas Medical Branch Claude D. Pepper Older Americans Independence Center; Sealy Center on Aging, The University of Texas Medical Branch, Galveston, Texas, USA.
Stephen C WaringEssentia Health, Duluth, Minnesota, USA.ORCID 0000-0002-9674-0083
Todd M ManiniDepartment of Aging and Geriatric Research, University of Florida, Gainesville, Florida, USA.
Lillian C MinUniversity of Michigan, Ann Arbor, Michigan, USA.
Jeanne TeresiResearch Division, Hebrew Home at Riverdale, RiverSpring Health, Bronx, New York, USA.
Patricia C DykesBrigham and Women's Hospital, Boston, Massachusetts, USA.
Siobhan McMahonSchool of Nursing, University of Minnesota, Minneapolis, Minnesota, USA.
Joanne M McGloinYale Claude D. Pepper Older Americans Independence Center, Yale University, New Haven, Connecticut, USA.
Eleni A SkokosYale Claude D. Pepper Older Americans Independence Center, Yale University, New Haven, Connecticut, USA.
Peter CharpentierYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.
Shehzad BasariaBoston Claude D. Pepper Older Americans Independence Center, Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Pamela W DuncanSchool of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.
Thomas W StorerBoston Claude D. Pepper Older Americans Independence Center, Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Priscilla GazarianBrigham and Women's Hospital, Boston, Massachusetts, USA.
Heather G AlloreYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.
James DziuraYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.
Denise EssermanYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.
Martha B CarnieBrigham and Women's Hospital, Boston, Massachusetts, USA.
Catherine HansonUniversity of Miami Health System, Miami, Florida, USA.
Fred KoIcahn School of Medicine at Mount Sinai, New York, New York, USA.
Neil M ResnickPittsburgh Claude D. Pepper Older Americans Independence Center, Division of Geriatrics and Gerontology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jocelyn WigginsUniversity of Michigan, Ann Arbor, Michigan, USA.
Charles LuYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.
Can MengYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.
Lori GoehringBoston Claude D. Pepper Older Americans Independence Center, Research Program in Men's Health: Aging and Metabolism, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Maureen FaganUniversity of Miami Health System, Miami, Florida, USA.
Rosaly Correa-de-AraujoNational Institute on Aging, Bethesda, Maryland, USA.
Carri CasteelUniversity of Iowa, Iowa City, Iowa, USA.
Peter PeduzziYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.
Erich J GreeneYale Center for Analytical Sciences, Yale University, New Haven, Connecticut, USA.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Albert C Shaw · 2002 to 2026
$37.9M
Wake Forest Claude D. Pepper OAIC - RenewalP30AG021332 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Denise Kathryn Houston · 2002 to 2026
$36.4M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Randomized Trial of a Multifactorial Fall Injury Prevention Strategy-SupplementU01AG048270 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI BHASIN, SHALENDER, GILL, THOMAS MICHAEL · 2014 to 2019
$34.8M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
UTMB OAIC Research Education Component (REC)P30AG024832 · NIA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI JAMES S. GOODWIN, MD, MELISSA M. MORROW · 2005 to 2026
$26.7M
TUFTS--FIELDINGP30AG031679 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI SHALENDER BHASIN · 2008 to 2026
$23.9M
NCATS NIH HHS KL2 TR000113NCATS NIH HHS UL1 TR000114NCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1 TR001102NCATS NIH HHS UL1 TR001863NCATS NIH HHS UL1 TR002541NIA NIH HHS K07 AG043587NIA NIH HHS K07AG043587NIA NIH HHS K08 AG050808NIA NIH HHS P30AG013679NIA NIH HHS P30 AG021332NIA NIH HHS P30AG021332NIA NIH HHS P30 AG021342NIA NIH HHS P30AG021342NIA NIH HHS P30 AG022845NIA NIH HHS P30 AG024824NIA NIH HHS P30AG024824NIA NIH HHS P30 AG024832NIA NIH HHS P30AG024832NIA NIH HHS P30 AG028741NIA NIH HHS P30 AG028747NIA NIH HHS P30 AG028748NIA NIH HHS P30AG028748NIA NIH HHS P30 AG031679NIA NIH HHS P30AG2874106NIA NIH HHS U01 AG048270NIA NIH HHS U01AG048270NIH HHS KL2TR000113NIH HHS UL1TR000114NIH HHS UL1TR000142NIH HHS UL1TR001102
6 · The paper itself

Abstract

BACKGROUND/

objectivesIn the Strategies to Reduce Injuries and Develop Confidence in Elders (STRIDE) study, a multifactorial intervention was associated with a nonsignificant 8% reduction in time to first serious fall injury but a significant 10% reduction in time to first self-reported fall injury relative to enhanced usual care. The effect of the intervention on other outcomes important to patients has not yet been reported. We aimed to evaluate the effect of the intervention on patient well-being including concern about falling, anxiety, depression, physical function, and disability.

designPragmatic cluster-randomized trial of 5,451 community-living persons at high risk for serious fall injuries.

settingA total of 86 primary care practices within 10 U.S. healthcare systems.

participantsA random subsample of 743 persons aged 75 and older. MEASUREMENTS: The well-being measures, assessed at baseline, 12 months, and 24 months, included a modified version of the Fall Efficacy Scale, Patient-Reported Outcomes Measurement Information System (PROMIS) anxiety and depression scales, and Late-Life Function and Disability Instrument.

resultsParticipants in the intervention (n = 384) and control groups (n = 359) were comparable in age: mean (standard deviation) of 81.9 (4.7) versus 81.8 (5.0) years. Mean scores were similar between groups at 12 and 24 months for concern about falling, physical function, and disability, whereas the intervention group's mean scores on anxiety and depression were .7 points lower (i.e., better) at 12 months and .6 to .8 points lower at 24 months. For each of these outcomes, differences between the groups' adjusted least square mean changes from baseline to 12 and 24 months, respectively, were quantitatively small. The overall difference in means between groups over 2 years was statistically significant only for depression, favoring the intervention: -1.19 (99% confidence interval, -2.36 to -.02), with 3.5 points representing a minimally important difference.

conclusionsSTRIDE's multifactorial intervention to reduce fall injuries was not associated with clinically meaningful improvements in patient well-being.

Indexed as

Accidental FallsNurse's RoleRisk AssessmentAged, 80 and overAnxietyDepressionFemaleHumansIndependent LivingMalePatient Reported Outcome MeasuresPatientsPrimary Health Carefall injury preventionolder personspragmatic trialswell-being

Identifiers

PMID33037632
PMCPMC8178516

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.