ReviewNeurosurgical review2021
Cervical spine manifestations of rheumatoid arthritis: a review.
Review in Neurosurgical review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Clinical characteristics of hypoglossal nerve palsy secondary to internal carotid artery dissection: a systematic review and illustrative case.Frontiers in neurologyPooled it
- Unilateral High-Riding Vertebral Artery Associates With the Progression of Atlantoaxial Joint Degeneration in Patients With Rheumatoid Arthritis.International journal of rheumatic diseases · 2026Observational
- Atlantoaxial instability in psoriatic arthritis: Frequency and correlated factors from a single-center cohort.Clinical rheumatology · 2026Article
- Rheumatoid Arthritis in the Cervical Spine: An Updated Review of Epidemiology, Imaging, and Surgical Indications.Spine surgery and related research · 2026Review
- Crowned Dens Syndrome associated with rheumatoid arthritis: A case report of two patients with a systematic literature review.Caspian journal of internal medicine · 2026Article
- Rheumatoid arthritis and risks of postoperative adverse events after posterior lumbar interbody fusion for lumbar degenerative diseases: a retrospective cohort study with matched controls.Frontiers in surgery · 2026Article
- Long-term outcomes of surgical treatment of cervical spine involvement in rheumatoid arthritis.International orthopaedics · 2025Article
- Change in the angle of cervical lordosis after occipito-cervical fixation in the course of instability of C1-C2 in patients with rheumatoid arthritis.Rheumatology international · 2025Article
- Atypical nucleus pulposus migration and calcification: A specific radiographic sign for lumbar rheumatoid spondylitis.PloS one · 2025Article
- Deep learning-based prediction of rheumatoid arthritis-associated deformity on MRI.Brain & spine · 2025Article
- Article
- Prevalence and location of inflammatory and structural lesions in patients with rheumatoid arthritis and radiographic axial spondyloarthritis with chronic neck pain evaluated by magnetic resonance imaging.Arthritis research & therapy · 2024Article
- Autoimmune diseases of the spine and spinal cord.The neuroradiology journal · 2024Review
- Hypoglossal Nerve Neuropathies-Analysis of Causes and Anatomical Background.Biomedicines · 2024Review
- Cefiderocol and Intraventricular Colistin for Ventriculitis due to an Extensively Drug-ResistantJournal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024Article
- The assessment of atlantoaxial joint involvement in patients with rheumatoid arthritis, results from an observational "real-life" study.Scientific reports · 2023Article
- Clinical features of atlantoaxial involvement in patients with rheumatoid arthritis usingClinical rheumatology · 2023Article
- Craniocervical junction involvement in inflammatory arthritis: a single-center radiologic study.Turkish journal of medical sciences · 2023Article
- Rheumatoid Diseases Involving the Cervical Spine I. History, Definition, and Diagnosis: New Trends and Technologies.Acta neurochirurgica. Supplement · 2023Review
- Increased Risk of Common Orthopedic Surgeries for Patients with Rheumatic Diseases in Taiwan.Medicina (Kaunas, Lithuania) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rheumatoid arthritis (RA) is a progressive autoimmune inflammatory disease affecting 1% of the population with three times as many women as men. As many as 86% of patients suffering from RA have cervical spine involvement. Synovial inflammation in the cervical spine causes instability and injuries including atlantoaxial subluxation, retroodontoid pannus formation, cranial settling, and subaxial subluxation. While many patients with cervical spine involvement are asymptomatic, symptomatic patients often present with nonspecific symptoms resulting from inflammation and additional secondary symptoms that are due to compression of the brainstem, cranial nerves, vertebral artery, and spinal cord. Radiographs are the imaging modality used most often, while MRI and CT are used for assessment of neural element involvement and surgical planning. Multiple classification systems exist. Early diagnosis and treatment of cervical spine involvement is critical. Surgical management is indicated when patients experience symptoms from cervical involvement that result in biomechanical instability and, or a neurological deficit. Atlantoaxial instability managed with atlantoaxial fusion, retroodontoid pannus with neural element compression is managed with posterior decompression and atlantoaxial fusion or occipitocervical fusion. Cranial settling is managed can be managed with anterior decompression and posterior fusion or with dorsal only approaches. Subaxial subluxation is managed with circumferential fusion or posterior only decompression and fusion. Patients with atlantoaxial instability have better functional and neurologic outcomes. RA patients have higher complication rates and more frequent need for revision surgery than the general population of spine surgery patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.