Evidence map›Paper›PMID 33037501›Full record

ReviewClinical research in cardiology : official journal of the German Cardiac Society2021

Thromboembolic complications in adult congenital heart disease: the knowns and the unknowns.

Clément Karsenty, Victor Waldmann, Barbara Mulder, Sébastien Hascoet, Magalie Ladouceur

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Sleep disordered breathing and adult congenital heart disease.International journal of cardiology. Congenital heart disease · 2024
    Review
  4. SomaticExperimental and therapeutic medicine · 2024
    Article
  5. Discovery ofAmerican journal of translational research · 2024
    Article
  6. Article
  7. Stroke and systemic embolism in adult congenital heart disease.International journal of cardiology. Congenital heart disease · 2023
    Review
  8. Cardiac Drugs in ACHD Cardiovascular Medicine.Journal of cardiovascular development and disease · 2023
    Review
  9. Article
  10. Identification ofDiagnostics (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Clément KarsentyPediatric and Congenital Cardiology, Centre Hospitalier Universitaire de Toulouse, Université de Toulouse, 330 Avenue de Grande Bretagne, 31300, Toulouse, France. karsenty.cl@chu-toulouse.fr.ORCID http://orcid.org/0000-0002-3303-5854
Victor WaldmannElectrophysiology Unit and Adult Congenital Heart Disease Unit, Department of Cardiology, European Georges Pompidou Hospital, APHP, Paris Descartes University, Paris, France.
Barbara MulderDepartment of Cardiology, Amsterdam University Medical Center, Location AMC, Meibergdreef 9, 1105AZ, Amsterdam, the Netherlands.
Sébastien HascoetDepartment of Congenital Heart Diseases, Centre de référence Des Malformations Cardiaques Congénitales Complexes M3C, Marie Lannelongue Hospital, Groupe Hospitalier Paris -Saint Joseph, Inserm U999, Paris-Sud University, Orsay, France.
Magalie Ladouceur *Centre de Recherche Cardiovasculaire de Paris, INSERM U970, Paris, France.
Hôpital Necker-Enfants Malades · FRInserm · FRUniversité Paris-Sud · FRUniversité Toulouse III - Paul Sabatier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite impressive improvement in long-term survival, adults with congenital heart disease (CHD) remain exposed to a significant cardiovascular morbidity over lifetime. Thromboembolic events (TE) are a major issue. Specific anatomic groups have been shown a particular high risk of TE, including cyanotic heart disease and Fontan circulation. Many intercurrent clinical factors add a substantial risk such as intracardiac medical devices, atrial arrhythmia, endocarditis, or pregnancy. Nevertheless, what is unknown exceeds what is known, especially regarding the management of this heterogenous patient population. Anticoagulation decision should always be individualized weighing balanced with the alternative risk of hemorrhagic complications. In this review, we aim to synthetize existing literature on TE in adults with CHD, discuss management issues, highlight gaps in knowledge, and intend to suggest high priority research.

Indexed as

AdultAnticoagulantsHeart Defects, CongenitalHemorrhageHumansRisk FactorsThromboembolismAnticoagulantsCongenital heart diseaseManagementStrokeThromboembolic events

Identifiers

PMID33037501
OpenAlexW3092276812

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.