ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2021
Does preoperative prognostic nutrition index predict surgical site infection after spine surgery?
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Do nutritional assessment tools (PNI, CONUT, GNRI) predict adverse events after spinal surgeries? A systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2024Pooled it
- A meta-analysis of risk factors for non-superficial surgical site infection following spinal surgery.BMC surgery · 2023Pooled it
- Composite inflammatory, immune, and nutritional indices for predicting surgical site infection following spine surgery: a systematic review with narrative synthesis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Prognostic nutritional index (PNI) is a predictor of adverse outcomes following open ventral hernia repair.Surgical endoscopy · 2026Article
- Risk factors for surgical site infections after spinal surgery: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Machine learning versus clinical scoring systems for predicting poor wound healing after posterior surgery for thoracolumbar tuberculosis.Journal of orthopaedic surgery and research · 2026Article
- Lower Limb Phase Angle Correlates Most with Locomotive Syndrome and Walking Function in Patients with Lumbar Spinal Stenosis: A Retrospective Study.Spine surgery and related research · 2026Article
- Preoperative geriatric nutritional risk index is a reliable tool for predicting postoperative adjacent segment disease among elderly patients with degenerative lumbar diseases: a case control study.BMC musculoskeletal disorders · 2026Article
- Preoperative prognostic nutritional index and its impact on surgical-site infection after cesarean section: a retrospective case-control analysis.Archives of gynecology and obstetrics · 2026Article
- Are cancer prognostic factors useful in predicting surgical site infections after spinal instrumentation surgery?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Prognostic nutritional index versus pragmatically operationalized GLIM criteria for predicting postoperative complications and recovery in spine surgery: a prospective cohort study.Frontiers in nutrition · 2026Article
- The value of perioperative nutritional risk stratification in the prevention of surgical site infection: precision application from GLIM/PG-SGA to PNI, CONUT, and GNRI.Frontiers in nutrition · 2026Review
- A prospective study on age-specific normative values of the prognostic nutritional index and the effects of malnutrition on spinal alignment using health checkup data of elderly residents.Asian spine journal · 2025Article
- Analysis of Outcomes in Pancreaticoduodenectomy for Elderly Patients Aged 80 and Above: A Retrospective Study Using Inverse Probability of Treatment Weighting.Aging medicine (Milton (N.S.W)) · 2025Article
- Impact of Nutritional Risk on Complications and Recovery in the Older People: A Geriatric Nutritional Risk Index-Based Study.Spine surgery and related research · 2025Article
- Article
- C-Reactive Protein to Albumin Ratio and Prognostic Nutrition Index as a Predictor of Periprosthetic Joint Infection and Early Postoperative Wound Complications in Patients Undergoing Primary Total Hip and Knee Arthroplasty.Diagnostics (Basel, Switzerland) · 2025Article
- The Impact of Preoperative Malnutrition on Postoperative Outcomes in Older Patients Undergoing Lumbar Decompression.Cureus · 2025Article
- The Association Between Comorbidities and Medical Complications for Adult Spinal Deformity Surgery: What Factors Have the Greatest Impact on Adverse Events and Outcomes?Global spine journal · 2025Article
- Incidence and risk factors of dysphagia after cervical laminoplasty.Scientific reports · 2025Observational
Corrections and comments
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Authors and funding
15 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMalnutrition is reported as one of the risk factors for surgical site infection (SSI). The prognostic nutritional index (PNI) is a simple method for nutritional evaluation. However, little is known about the relationship between SSI and the PNI in patients after spine surgery. We aimed to determine independent predictors of SSI after spine surgery.
methodsWe analyzed 1115 patients who underwent spine surgery (369 males, 746 females, mean age 56 years, follow-up period: at least 1 year). Patients were divided into SSI and non-SSI groups. Preoperative risk factors, including PNI (10 × serum albumin [g/dL] + 0.005 × total lymphocyte count [/μL]), were assessed.
resultsPostoperatively, 43 patients (3.9%) experienced SSI. Univariate analysis showed that preoperative PNI (48.5 vs 51.7; p < 0.01), revision status (p < 0.05), male sex (p < 0.01), body mass index (BMI) (p < 0.05), and usage of anticoagulant agents (p < 0.05) differed significantly between the SSI and non-SSI groups. Multivariate logistic regression analysis showed that preoperative PNI (odds ratio [OR], 0.94; 95% confidence interval [CI]: 0.90-0.98; p < 0.01), male sex (OR, 2.64; 95% CI: 1.40-4.99; p < 0.01), length of surgery ≥ 180 min (OR, 2.78; 95% CI: 1.30-5.96; p < 0.01), BMI ≥ 30 kg/m
conclusionLower preoperative PNI was found to be a risk factor for SSI after spine surgery. Patients with lower preoperative PNI values should be cautioned about the risk of SSI and provide adequate informed consent.
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