Evidence map›Paper›PMID 33037310›Full record

ArticleScientific reports2020

The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV.

Mihkel Örd, Ilona Faustova, Mart Loog

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers.

0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed
3.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

110 citing papers in PubMed, 187 citations in OpenAlex.

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  19. Structural proteins of human coronaviruses: what makes them different?Frontiers in cellular and infection microbiology · 2024
    Review
  20. Article

50 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mihkel ÖrdInstitute of Technology, University of Tartu, 50411, Tartu, Estonia.
Ilona FaustovaInstitute of Technology, University of Tartu, 50411, Tartu, Estonia.
Mart LoogInstitute of Technology, University of Tartu, 50411, Tartu, Estonia. mart.loog@ut.ee.
University of Tartu · EE

Funding

Tartu Ülikool PLTTI20909
6 · The paper itself

Abstract

The Spike protein of the novel coronavirus SARS-CoV2 contains an insertion

Indexed as

Amino Acid MotifsAmino Acid SequenceBetacoronavirusFurinMiddle East Respiratory Syndrome CoronavirusPhosphorylationProteolysisSARS-CoV-2Severe acute respiratory syndrome-related coronavirusSpike Glycoprotein, CoronavirusVirus InternalizationFurinSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2

Identifiers

PMID33037310
PMCPMC7547067
OpenAlexW3091938242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.