Evidence map›Paper›PMID 33037280›Full record

SynthesisScientific reports2020

Dose-response-relationship of stabilisation exercises in patients with chronic non-specific low back pain: a systematic review with meta-regression.

Juliane Mueller, Daniel Niederer

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05905562 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Core Muscle Activation Exercise Training Program on Pain, Range of Motion, and Function in Patients With Chronic Low Back Pain

TypeinterventionalSponsorRiphah International UniversityRan2023 to 2023Enrolled34ConditionsLow Back PainArmscore stabilization exercises, Spinal mobilization techniques
NCT06295276 nacompletednot on this mapstarted 2024, after this paper: background citation

Does a Teletherapy-guided Exercise Programme Improve Pain Intensity, Disability, and Quality of Life in Nursing Students With Back and Neck Pain Compared to a Control Group?

TypeinterventionalSponsorHochschule OsnabruckRan2024 to 2024Enrolled48ConditionsLow Back Pain, Neck PainArmsteletherapy-guided exercise programme, Waiting list/control intervention/delayed teletherapy intervention
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Effects of combined trunk stretching and lumbar stabilization exercises for chronic non-specific low back pain: a randomized clinical trial.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Trial
  4. Trial
  5. Trial
  6. Chronic Ankle Instability and Low Back Pain: A Narrative Review With a Conceptual Framework Linking Distal and Proximal Sensorimotor Dysfunction.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Exercise Prescription for Patients With Persistent Low Back Pain Who Present With Impaired Lateral Abdominal Muscle Activation: A Delphi Survey.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Preoperative conservative treatment is insufficiently described in clinical trials of lumbar fusion: a scoping review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Juliane MuellerDepartment of Computer Science | Therapy Sciences, Professorship for Physiotherapy: Exercise Science and Applied Biomechanics, Trier University of Applied Sciences, Trier, Germany.
Daniel NiedererDepartment of Sports Medicine and Exercise Physiology, Goethe University Frankfurt, Frankfurt am Main, Germany. niederer@sport.uni-frankfurt.de.
Goethe University Frankfurt · DETrier University of Applied Sciences · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stabilization exercise (SE) is evident for the management of chronic non-specific low back pain (LBP). The optimal dose-response-relationship for the utmost treatment success is, thus, still unknown. The purpose is to systematically review the dose-response-relationship of stabilisation exercises on pain and disability in patients with chronic non-specific LBP. A systematic review with meta-regression was conducted (Pubmed, Web of Knowledge, Cochrane). Eligibility criteria were RCTs on patients with chronic non-specific LBP, written in English/German and adopting a longitudinal core-specific/stabilising/motor control exercise intervention with at least one outcome for pain intensity and/or disability. Meta-regressions (dependent variable = effect sizes (Cohens d) of the interventions (for pain and for disability), independent variable = training characteristics (duration, frequency, time per session)), and controlled for (low) study quality (PEDro) and (low) sample sizes (n) were conducted to reveal the optimal dose required for therapy success. From the 3,415 studies initially selected, 50 studies (n = 2,786 LBP patients) were included. N = 1,239 patients received SE. Training duration was 7.0 ± 3.3 weeks, training frequency was 3.1 ± 1.8 sessions per week with a mean training time of 44.6 ± 18.0 min per session. The meta-regressions' mean effect size was d = 1.80 (pain) and d = 1.70 (disability). Total R

Indexed as

Chronic PainExerciseExercise TherapyHumansLow Back Pain

Identifiers

PMID33037280
PMCPMC7547082
OpenAlexW3092088135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.