ArticleScientific reports2020
Altered metabolomic profiling of overweight and obese adolescents after combined training is associated with reduced insulin resistance.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 9 of them syntheses that pooled it.
What it found
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Who cites it
28 citing papers in PubMed, 9 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Physical Activity and Metabolic Alterations in Children and Adolescents Across Different Weight Groups: A Systematic Review.European journal of sport science · 2026Pooled it
- Combined aerobic and resistance exercise improves glucose metabolism and insulin resistance in children and adolescents with overweight or obesity: a meta-analysis.Scientific reports · 2026Pooled it
- Effects of exercise on cardiorespiratory fitness in children and adolescents with overweight and obesity: a systematic review and meta-analysis of 72 randomized controlled trials.BMC public health · 2025Pooled it
- Effects of different physical exercise programs on blood pressure in overweight children and adolescents: systematic review and meta-analysis.BMC pediatrics · 2025Pooled it
- Pooled it
- Effects of aerobic exercise combined with resistance training on body composition and metabolic health in children and adolescents with overweight or obesity: systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Effects of different exercise modalities and intensities on body composition in overweight and obese children and adolescents: a systematic review and network meta-analysis.Frontiers in physiology · 2023Pooled it
- The Metabolic Signature of Cardiorespiratory Fitness: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2022Pooled it
- Fat-free/lean body mass in children with insulin resistance or metabolic syndrome: a systematic review and meta-analysis.BMC pediatrics · 2022Pooled it
- Effects of breaking up prolonged sitting via exercise snacks intervention on the body composition and plasma metabolomics of sedentary obese adults: a randomized controlled trial.Endocrine journal · 2025Trial
- Combined training increases thermogenic fat activity in patients with overweight and type 2 diabetes.International journal of obesity (2005) · 2022Trial
- Comparative effects of exercise modalities on ectopic fat reduction in overweight and obese children and adolescents: a narrative review.European journal of pediatrics · 2026Review
- A vegan diet signature from a multi-omics study on different European populations is related to favorable metabolic outcomes.Gut microbes · 2025Observational
- Interventional approaches to combat obesity: Exploring the metabolomic signature of weight loss trials.Metabolism open · 2025Review
- Lipids as key biomarkers in unravelling the pathophysiology of obesity-related metabolic dysregulation.Heliyon · 2025Article
- Effects of Different Exercise Interventions on Health Status in Overweight and Obese Children and Adolescents: A Network Meta-Analysis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Advancing pediatric exercise research: A focus on immunomics and cutting-edge technologies.Journal of sport and health science · 2024Article
- The effect of high-intensity interval training on type 2 diabetic muscle: A metabolomics-based study.Heliyon · 2024Article
- Moderate-intensity Combined Training Induces Lipidomic Changes in Individuals With Obesity and Type 2 Diabetes.The Journal of clinical endocrinology and metabolism · 2024Article
- Effects of exercise training on glucose metabolism indicators and inflammatory markers in obese children and adolescents: A meta-analysis.World journal of diabetes · 2024Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exercise training and a healthy diet are the main non-pharmacological strategies for treating chronic conditions, such as obesity and insulin resistance (IR), in adolescents. However, the isolated metabolic changes caused by exercise training without dietary intervention have not yet been established. We investigated how combined training (CT) without dietary intervention altered the concentrations of serum metabolites, biochemical, anthropometric and functional parameters in overweight and obese adolescents. Thirty-seven adolescents (14.6 ± 1.05 years), of both sexes, were randomly assigned to the control group (CG, n = 19) or the training group (TG, n = 18). The CT was composed by resistance training and aerobic training performed in the same session (~ 60 min), three times a week, for 12 weeks. All assessments were performed pre and post-intervention. Metabolomics analyses were conducted using nuclear magnetic resonance spectroscopy (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.