Evidence map›Paper›PMID 33037255›Full record

Trial reportScientific reports2020

Effect of warming eyelids on tear film stability and quality of life in visual display terminal users: a randomized controlled trial.

Chi-Chin Sun, Chia-Yi Lee, Yih-Shiou Hwang, Igaki Michihito, Kyoko Tagami, Ching-Hsi Hsiao

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Meibomian Gland Dysfunction Clinical Practice Guidelines.Japanese journal of ophthalmology · 2023
    Article
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Chi-Chin SunDepartment of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan.
Chia-Yi LeeDepartment of Ophthalmology, Show Chwan Memorial Hospital, Changhua, Taiwan.
Yih-Shiou HwangDepartment of Medicine, School of Medicine, Chang Gung University, Taoyüan, Taiwan.
Igaki MichihitoPersonal Health Care Products Research Laboratories, Kao Corporation, Sumida-ku, Tokyo, Japan.
Kyoko TagamiPersonal Health Care Products Research Laboratories, Kao Corporation, Sumida-ku, Tokyo, Japan.
Ching-Hsi HsiaoDepartment of Medicine, School of Medicine, Chang Gung University, Taoyüan, Taiwan. hsiao.chinghsi@gmail.com.
Chang Gung Memorial Hospital · TWKao Corporation (Japan) · JPChang Bing Show Chwan Memorial Hospital · TWChang Gung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to evaluate the effect of warming eyelids on tear-film stability and quality of life (QoL) in video display terminal (VDT) users. A prospective study was conducted and 45 volunteers with ocular symptoms and tear-film instability associated with VDT use were randomly allocated into the study (n = 22) or control groups (n = 23). Subjects in the study group used eyelid warming steamer (EWS) for 2 weeks and tear fluorescein breakup time (TBUT) after single and 2-week EWS treatment, Schirmer I test, ocular surface staining scores, meibomian gland assessment, severity of dry eye disease (DED) and QoL scores after 2-week EWS treatment were analysed. The TBUT improved after both single and 2-week EWS treatment (P = 0.023 and 0.027, respectively) in the study group. The ocular surface staining scores were significantly decreased only in the study group (P = 0.038). About 60% DED patients in the study group shifted towards non-DED and the pattern of distribution was significantly different compared to baseline (P < 0.001). The QoL scores significantly improved in the study group (P = 0.002) with a negative correlation with TBUT. In conclusion, in VDT users with short TBUT, eyelid warming steamer is effective in improving tear-film stability and QoL.

Indexed as

AdultDry Eye SyndromesEyelidsFemaleFluoresceinHumansMaleMeibomian GlandsProspective StudiesQuality of LifeTearsVision, OcularFluorescein

Identifiers

PMID33037255
PMCPMC7547003
OpenAlexW3091785378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.