Evidence map›Paper›PMID 33037133›Full record

ArticleJournal of lipid research2020

Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.

Gerhard Liebisch, Eoin Fahy, Junken Aoki, Edward A Dennis, Thierry Durand, Christer S Ejsing, Maria Fedorova, Ivo Feussner, William J Griffiths, Harald Köfeler and 7 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 439 papers.

0numbers the graph read from it
0cells of the map it votes in
439citing papers in PubMed
32.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

439 citing papers in PubMed, 819 citations in OpenAlex.

  1. Trial
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  9. Physio-Morphological Assessment and Multi-Omics Analysis ofJournal of fungi (Basel, Switzerland) · 2026
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  16. FASEB bioAdvances · 2026
    Article
  17. Article
  18. Article
  19. Review
  20. Article

379 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 14 institutions in 7 countries.

Gerhard LiebischInstitute of Clinical Chemistry and Laboratory Medicine, Regensburg University Hospital, Regensburg, Germany.
Eoin FahyDepartment of Bioengineering, University of California San Diego, La Jolla, CA, USA.
Junken AokiGraduate School of Pharmaceutical Sciences, University of Tokyo, Bunkyo-ku, Tokyo, Japan.
Edward A DennisDepartment of Chemistry and Biochemistry, Department of Pharmacology, School of Medicine, University of California San Diego, La Jolla, CA, USA.
Thierry DurandInstitute of Biomolecules Max Mousseron, University of Montpellier, CNRS, ENSCM, Montpellier, France.
Christer S EjsingDepartment of Biochemistry and Molecular Biology, Villum Center for Bioanalytical Sciences, University of Southern Denmark, Odense, Denmark; Cell Biology and Biophysics Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Maria FedorovaInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, Leipzig, Germany; Center for Biotechnology and Biomedicine, University of Leipzig, Leipzig, Germany.
Ivo FeussnerDepartment of Plant Biochemistry, Albrecht-von-Haller-Institute and Göttingen Center for Molecular Biosciences (GZMB), University of Göttingen, Göttingen, Germany.
William J GriffithsSwansea University Medical School, Swansea, United Kingdom.
Harald KöfelerCore Facility Mass Spectrometry, Medical University of Graz, Graz, Austria.
Alfred H MerrillSchool of Biological Sciences and the Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA.
Robert C MurphyDepartment of Pharmacology, University of Colorado at Denver, Aurora, CO, USA.
Valerie B O'DonnellSystems Immunity Institute, Cardiff University, Cardiff, United Kingdom.
Olga OskolkovaInstitute of Pharmaceutical Sciences, University of Graz, Graz, Austria.
Shankar SubramaniamDepartment of Biomedical Engineering, Jacobs School of Engineering, University of California San Diego, La Jolla, CA, USA.
Michael J O WakelamBabraham Institute, Babraham Research Campus, Cambridge, United Kingdom.
Friedrich SpenerDepartment of Molecular Biosciences, University of Graz, Graz, Austria; Division of Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria. Electronic address: fritz.spener@uni-graz.at.
University of California San Diego · USUniversity of Graz · ATBabraham Institute · GBCardiff University · GBÉcole Nationale Supérieure de Chimie de Montpellier · FRGeorgia Institute of Technology · USLeipzig University · DEMedical University of Graz · ATSwansea University · GBThe University of Tokyo · JPUniversity Hospital Regensburg · DEUniversity of Colorado Denver · USUniversity of Göttingen · DEUniversity of Southern Denmark · DK

Funding

STEROL LIPIDSU54GM069338 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DENNIS, EDWARD A · 2003 to 2013
$72.2M
NIGMS NIH HHS U54 GM069338Wellcome Trust 203014/Z/16/Z
6 · The paper itself

Abstract

A comprehensive and standardized system to report lipid structures analyzed by MS is essential for the communication and storage of lipidomics data. Herein, an update on both the LIPID MAPS classification system and shorthand notation of lipid structures is presented for lipid categories Fatty Acyls (FA), Glycerolipids (GL), Glycerophospholipids (GP), Sphingolipids (SP), and Sterols (ST). With its major changes, i.e., annotation of ring double bond equivalents and number of oxygens, the updated shorthand notation facilitates reporting of newly delineated oxygenated lipid species as well. For standardized reporting in lipidomics, the hierarchical architecture of shorthand notation reflects the diverse structural resolution powers provided by mass spectrometric assays. Moreover, shorthand notation is expanded beyond mammalian phyla to lipids from plant and yeast phyla. Finally, annotation of atoms is included for the use of stable isotope-labeled compounds in metabolic labeling experiments or as internal standards. This update on lipid classification, nomenclature, and shorthand annotation for lipid mass spectra is considered a standard for lipid data presentation.

Indexed as

LipidomicsLipidsMass SpectrometryAnimalsHumansTerminology as TopicLipidsfatty acylsglycerolipidsglycerophospholipidslipidomicsmass spectrometrysphingolipidssterols

Identifiers

PMID33037133
PMCPMC7707175
OpenAlexW3091953196

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.