Evidence map›Paper›PMID 33037131›Full record

ArticleJournal of the American Society of Nephrology : JASN2020

Major Variation across Local Transplant Centers in Probability of Kidney Transplant for Wait-Listed Patients.

Kristen L King, S Ali Husain, Jesse D Schold, Rachel E Patzer, Peter P Reese, Zhezhen Jin, Lloyd E Ratner, David J Cohen, Stephen O Pastan, Sumit Mohan

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Outcomes of Deceased Donor Kidney Transplants Allocated Out of Sequence in the United States.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Observational
  7. Review
  8. Article
  9. Article
  10. Out-of-Sequence Placement of Deceased Donor Kidneys Is Exacerbating Inequities in the United States.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Article
  11. Article
  12. Association between out-of-sequence allocation and deceased donor kidney nonuse across organ procurement organizations.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  13. Decreasing efficiency in deceased donor kidney offer notifications under the new distance-based kidney allocation system.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  14. Review
  15. Review
  16. The dynamics of deceased donor kidney transplant decision making: insights from studying individual clinicians' offer decisions.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  17. Article
  18. Transforming transplantation access: A federal directive for comprehensive pre-waitlisting data collection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kristen L KingDivision of Nephrology, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
S Ali HusainDivision of Nephrology, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Jesse D ScholdCenter for Populations Health Research, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.
Rachel E PatzerDepartment of Surgery, Emory University School of Medicine, Atlanta, Georgia.
Peter P ReeseRenal-Electrolyte and Hypertension Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0003-1440-069X
Zhezhen JinDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York.
Lloyd E RatnerDepartment of Surgery, Columbia University College of Physicians and Surgeons and New York Presbyterian Hospital, New York, New York.
David J CohenDivision of Nephrology, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York.
Stephen O PastanRenal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.ORCID 0000-0003-2638-6354
Sumit MohanDivision of Nephrology, Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, New York sm2206@cumc.columbia.edu.ORCID 0000-0002-5305-9685

Funding

Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6M
5/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical CenterU01DK116066 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Sumit Mohan, Deirdre Sawinski · 2017 to 2026
$2.5M
Identifying and exploring solutions to the ethical challenges of ApoL1 testing of donors with recent African ancestry through mixed methods research with stakeholdersR01MD014161 · NIMHD · WASHINGTON UNIVERSITY · PI DUBOIS, JAMES M, MOHAN, SUMIT · 2019 to 2021
$1.2M
Increasing Minority Population Awareness through Community Teaching for Improved Organ Donation (IMPACT for Improved Organ Donation)R01DK114893 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MOHAN, SUMIT · 2017 to 2021
$1.2M
NCATS NIH HHS KL2 TR001874NIDDK NIH HHS R01 DK114893NIDDK NIH HHS U01 DK116066NIMHD NIH HHS R01 MD014161
6 · The paper itself

Abstract

backgroundGeographic disparities in access to deceased donor kidney transplantation persist in the United States under the Kidney Allocation System (KAS) introduced in 2014, and the effect of transplant center practices on the probability of transplantation for wait-listed patients remains unclear.

methodsTo compare probability of transplantation across centers nationally and within donation service areas (DSAs), we conducted a registry study that included all United States incident adult kidney transplant candidates wait listed in 2011 and 2015 (pre-KAS and post-KAS cohorts comprising 32,745 and 34,728 individuals, respectively). For each center, we calculated the probability of deceased donor kidney transplantation within 3 years of wait listing using competing risk regression, with living donor transplantation, death, and waiting list removal as competing events. We examined associations between center-level and DSA-level characteristics and the adjusted probability of transplant.

resultsCandidates received deceased donor kidney transplants within 3 years of wait listing more frequently post-KAS (22%) than pre-KAS (19%). Nationally, the probability of transplant varied 16-fold between centers, ranging from 4.0% to 64.2% in the post-KAS era. Within DSAs, we observed a median 2.3-fold variation between centers, with up to ten-fold and 57.4 percentage point differences. Probability of transplantation was correlated in the post-KAS cohort with center willingness to accept hard-to-place kidneys (

conclusionsLarge differences in the adjusted probability of deceased donor kidney transplantation persist under KAS, even between centers working with the same local organ supply. Probability of transplantation is significantly associated with organ offer acceptance patterns at transplant centers, underscoring the need for greater understanding of how centers make decisions about organs offered to wait-listed patients and how they relate to disparities in access to transplantation.

Indexed as

Waiting ListsAdultAgedCohort StudiesFemaleHumansKidney Failure, ChronicKidney TransplantationMaleMiddle AgedProbabilityTime FactorsTissue and Organ ProcurementUnited Stateshealth policykidney transplantationorgan allocationpatient preferencesshared decision-making

Identifiers

PMID33037131
PMCPMC7790218

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.