Evidence map›Paper›PMID 33036972›Full record

ArticleScience advances2020

NAD

Sivan Subburaju, Sarah Kaye, Yong Kee Choi, Jugajyoti Baruah, Debkanya Datta, Jun Ren, Ashwin Srinivasan Kumar, Gabor Szabo, Dai Fukumura, Rakesh K Jain and 2 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Sivan SubburajuAngiogenesis and Brain Development Laboratory, Huntington Medical Research Institutes (HMRI), 686 S Fair Oaks Avenue, Pasadena, CA 91105, USA.ORCID 0000-0003-3111-9859
Sarah KayeAngiogenesis and Brain Development Laboratory, Huntington Medical Research Institutes (HMRI), 686 S Fair Oaks Avenue, Pasadena, CA 91105, USA.
Yong Kee ChoiAngiogenesis and Brain Development Laboratory, Huntington Medical Research Institutes (HMRI), 686 S Fair Oaks Avenue, Pasadena, CA 91105, USA.ORCID 0000-0003-4411-3587
Jugajyoti BaruahAngiogenesis and Brain Development Laboratory, Huntington Medical Research Institutes (HMRI), 686 S Fair Oaks Avenue, Pasadena, CA 91105, USA.ORCID 0000-0003-2952-4943
Debkanya DattaAngiogenesis and Brain Development Laboratory, Huntington Medical Research Institutes (HMRI), 686 S Fair Oaks Avenue, Pasadena, CA 91105, USA.
Jun RenEdwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.ORCID 0000-0002-6358-0765
Ashwin Srinivasan KumarEdwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.ORCID 0000-0003-3251-9977
Gabor SzaboInstitute of Experimental Medicine, Medical Gene Technology Unit, 1083 Budapest, Hungary.ORCID 0000-0001-5438-5151
Dai FukumuraEdwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.ORCID 0000-0002-9505-4444
Rakesh K JainEdwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.ORCID 0000-0001-7571-3548
Abdallah ElkhalDepartment of Surgery, Harvard Medical School, Boston, MA 02115, USA.
Anju VasudevanAngiogenesis and Brain Development Laboratory, Huntington Medical Research Institutes (HMRI), 686 S Fair Oaks Avenue, Pasadena, CA 91105, USA. anju.vasudevan@hmri.org.ORCID 0000-0001-9814-2389
Huntington Medical Research Institutes · USHarvard University · USBrigham and Women's Hospital · USHUN-REN Institute of Experimental Medicine · HU

Funding

Dissecting Pediatric Brain Tumor Microenvironment to Improve TreatmentR35CA197743 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI JAIN, RAKESH K. · 2015 to 2020
$5.7M
Novel Developmental Pathways Underlying Psychiatric DisordersR01MH110438 · NIMH · MCLEAN HOSPITAL · PI Anju Vasudevan · 2016 to 2026
$4.7M
Reengineering obesity-induced abnormal microenvironment to improve PDAC treatmentR01CA208205 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI FUKUMURA, DAI, JAIN, RAKESH K. · 2017 to 2020
$2.2M
Novel Autonomous Roles of CNS AngiogenesisR01NS100808 · NINDS · MCLEAN HOSPITAL · PI VASUDEVAN, ANJU · 2017 to 2021
$1.7M
NCI NIH HHS R01 CA208205NCI NIH HHS R35 CA197743NCI NIH HHS U01 CA224173NIMH NIH HHS R01 MH110438NINDS NIH HHS R01 NS100808
6 · The paper itself

Abstract

Intrinsic defects within blood vessels from the earliest developmental time points can directly contribute to psychiatric disease origin. Here, we show that nicotinamide adenine dinucleotide (NAD

Indexed as

Endothelial CellsNADAnimalsFemaleGABAergic NeuronsMiceMice, KnockoutPregnancyProsencephalonReceptors, GABA-ANADReceptors, GABA-A

Identifiers

PMID33036972
PMCPMC7546698
OpenAlexW3092512009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.