Evidence map›Paper›PMID 33036940›Full record

ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2021

Mediators of suicidality 12 years after bariatric surgery relative to a nonsurgery comparison group.

Jacob G Mabey, Ronette L Kolotkin, Ross D Crosby, Sheila E Crowell, Steven C Hunt, Lance E Davidson

Abstract read
In one paragraph

Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Quality of Life after Bariatric Surgery-A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jacob G MabeyDepartment of Exercise Sciences, Brigham Young University, Provo, Utah. Electronic address: jacobmabey@gmail.com.
Ronette L KolotkinQuality of Life Consulting, Durham, North Carolina; Duke Family Medicine and Community Health, Duke University School of Medicine, Durham, North Carolina; Faculty of Health and Social Sciences, Western Norway University of Applied Sciences, Førde, Norway; Centre of Health Research, Førde Hospital Trust, Førde, Norway; Morbid Obesity Centre, Vestfold Hospital Trust, Tønsberg, Norway.
Ross D CrosbySanford Center for Biobehavioral Research, Sanford Research, Fargo, North Dakota; Department of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota.
Sheila E CrowellDepartment of Psychology, University of Utah, Salt Lake City, Utah; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, Utah; Department of Obstetrics & Gynecology, University of Utah School of Medicine, Salt Lake City, Utah.
Steven C HuntDepartment of Genetic Medicine, Weill Cornell Medicine, Doha, Qatar; Division of Epidemiology, University of Utah School of Medicine, Salt Lake City, Utah.
Lance E DavidsonDepartment of Exercise Sciences, Brigham Young University, Provo, Utah.

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
MORBIDITY/MORTALITY RELATED TO GASTRIC BYPASS SURGERYR01DK055006 · NIDDK · UNIVERSITY OF UTAH · PI HOPKINS, PAUL N · 2000 to 2014
$7.8M
Role of Nuclear IGFBP-3 in the Induction of Human Prostate Cancer Cell ApoptosisZ01DK055006 · NIDDK · DIABETES, DIGESTIVE, KIDNEY DISEASES · PI RECHLER, MATTHEW M · 1986 to 2007
$323k
Intramural NIH HHS Z01 DK055006NCATS NIH HHS UL1 TR002538NIDDK NIH HHS R01 DK055006
6 · The paper itself

Abstract

backgroundIndividuals undergoing bariatric surgery report higher levels of suicidality than the general population, but it is unknown what mediates this phenomenon or how this compares with individuals with severe obesity not receiving surgery.

objectivesWe evaluated suicidality in 131 individuals 12 years post surgery compared with 205 individuals with severe obesity who did not undergo surgery. Changes in health-related quality of life (HRQOL) and metabolic health were assessed as mediators of suicidality.

settingUniversity.

methodsSuicidality was assessed with the Suicide Behaviors Questionnaire-Revised at 12 years. Metabolic health and HRQOL (Short Form-36 [SF-36] Mental Component Summary score, Physical Component Summary score, and Impact of Weight on Quality of Life-Lite) were assessed at baseline and 2 and 6 years. The effects of bariatric surgery on suicidality at 12 years were assessed through univariate and multivariate sequential moderated mediation models, with changes in metabolic health and HRQOL from 0-2 years and 2-6 years as mediators.

resultsSuicidality was higher in the surgery group versus the nonsurgery group (estimate [est.] = .708, SE = .292, P < .05). Only the indirect pathways at 2 years after surgery for SF-36 Mental Component Summary in the univariate models (est. = -.172, SE = .080, P < .05) and for SF-36 Physical Component Summary in the multivariate model (est. = .593, SE = .281, P < .05) were significant.

conclusionIndividuals undergoing bariatric surgery reported higher levels of suicidality at 12 years, which was mediated by less improvement in the mental and physical components of HRQOL in the first 2 years after surgery, suggesting the need for additional clinical monitoring.

Indexed as

Bariatric SurgeryObesity, MorbidSuicideHumansQuality of LifeSurveys and QuestionnairesBariatric surgeryImpact of Weight on Quality of Life-Lite (IWQOL-Lite)Mediation analysisShort Form-36 (SF-36)SuicidalitySuicide Behaviors Questionnaire-Revised (SBQ-R)Utah Obesity Study

Identifiers

PMID33036940
PMCPMC7769914

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.