Evidence map›Paper›PMID 33036621›Full record

ArticleBMC health services research2020

Deceased donor kidney allocation: an economic evaluation of contemporary longevity matching practices.

Sameera Senanayake, Nicholas Graves, Helen Healy, Keshwar Baboolal, Adrian Barnett, Matthew P Sypek, Sanjeewa Kularatna

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sameera SenanayakeAustralian Center for Health Service Innovation, Queensland University of Technology, 60 Musk Ave, Kelvin Grove, QLD, 4059, Australia. sameerajayan.senanayake@hdr.qut.edu.au.ORCID https://orcid.org/0000-0002-5606-2046
Nicholas GravesAustralian Center for Health Service Innovation, Queensland University of Technology, 60 Musk Ave, Kelvin Grove, QLD, 4059, Australia.ORCID https://orcid.org/0000-0002-5559-3267
Helen HealyRoyal Brisbane Hospital for Women, Brisbane, Australia.ORCID https://orcid.org/0000-0003-4342-5300
Keshwar BaboolalRoyal Brisbane Hospital for Women, Brisbane, Australia.ORCID https://orcid.org/0000-0002-3688-9353
Adrian BarnettAustralian Center for Health Service Innovation, Queensland University of Technology, 60 Musk Ave, Kelvin Grove, QLD, 4059, Australia.ORCID https://orcid.org/0000-0001-6339-0374
Matthew P SypekAustralia and New Zealand Dialysis and Transplant (ANZDATA) Registry, Adelaide, SA, Australia.
Sanjeewa KularatnaAustralian Center for Health Service Innovation, Queensland University of Technology, 60 Musk Ave, Kelvin Grove, QLD, 4059, Australia.ORCID https://orcid.org/0000-0001-5650-154X
Queensland University of Technology · AUThe University of Queensland · AUAustralia and New Zealand Dialysis and Transplant Registry · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMatching survival of a donor kidney with that of the recipient (longevity matching), is used in some kidney allocation systems to maximize graft-life years. It is not part of the allocation algorithm for Australia. Given the growing evidence of survival benefit due to longevity matching based allocation algorithms, development of a similar kidney allocation system for Australia is currently underway. The aim of this research is to estimate the impact that changes to costs and health outcomes arising from 'longevity matching' on the Australian healthcare system.

methodsA decision analytic model to estimate cost-effectiveness was developed using a Markov process. Four plausible competing allocation options were compared to the current kidney allocation practice. Models were simulated in one-year cycles for a 20-year time horizon, with transitions through distinct health states relevant to the kidney recipient. Willingness to pay was considered as AUD 28000.

resultsBase case analysis indicated that allocating the worst 20% of Kidney Donor Risk Index (KDRI) donor kidneys to the worst 20% of estimated post-transplant survival (EPTS) recipients (option 2) and allocating the oldest 25% of donor kidneys to the oldest 25% of recipients are both cost saving and more effective compared to the current Australian allocation practice. Option 2, returned the lowest costs, greatest health benefits and largest gain to net monetary benefits (NMB). Allocating the best 20% of KDRI donor kidneys to the best 20% of EPTS recipients had the lowest expected incremental NMB.

conclusionOf the four longevity-based kidney allocation practices considered, transplanting the lowest quality kidneys to the worst kidney recipients (option 2), was estimated to return the best value for money for the Australian health system.

Indexed as

Kidney TransplantationAustraliaCost-Benefit AnalysisHealth Care CostsHumansLongevityMarkov ChainsResource AllocationTissue DonorsTransplant RecipientsCost utility analysisKidney allocationLongevity matchingQALYTransplant

Identifiers

PMID33036621
PMCPMC7547436
OpenAlexW3092284642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.