Evidence map›Paper›PMID 33036600›Full record

ArticleBMC oral health2020

Candida prevalence and oral hygiene due to orthodontic therapy with conventional brackets.

Kinga Grzegocka, Paweł Krzyściak, Anna Hille-Padalis, Jolanta E Loster, Katarzyna Talaga-Ćwiertnia, Bartłomiej W Loster

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kinga GrzegockaDepartment of Orthodontics, Dental Institute, Faculty of Medicine, Jagiellonian University Medical College, ul. Montelupich 4/108, 31-155, Kraków, Poland. kinga.grzegocka@uj.edu.pl.ORCID 0000-0002-9177-9544
Paweł KrzyściakDepartment of Mycology, Chair of Microbiology, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland.ORCID 0000-0002-2554-9409
Anna Hille-PadalisDepartment of Orthodontics, Dental Institute, Faculty of Medicine, Jagiellonian University Medical College, ul. Montelupich 4/108, 31-155, Kraków, Poland.ORCID 0000-0002-9244-9301
Jolanta E LosterDepartment of Prosthodontics, Dental Institute, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland.ORCID 0000-0002-8759-0810
Katarzyna Talaga-ĆwiertniaDepartment of Mycology, Chair of Microbiology, Faculty of Medicine, Jagiellonian University Medical College, Kraków, Poland.ORCID 0000-0003-0811-9295
Bartłomiej W LosterDepartment of Orthodontics, Dental Institute, Faculty of Medicine, Jagiellonian University Medical College, ul. Montelupich 4/108, 31-155, Kraków, Poland.ORCID 0000-0001-5724-5808
Jagiellonian University · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego K/ZDS/003737
6 · The paper itself

Abstract

backgroundConventional brackets are often used during orthodontic therapy of patients with malocclusion. The complex construction of such brackets greatly inhibits oral hygiene, which predisposes to increased carriage of microbiota. Orthodontic brackets could act as reservoir of yeast and predispose to oral candidosis. The aim of this study was to assess Candida prevalence and the role of oral hygiene during fixed appliance therapy. A further aim was to characterize the isolated yeasts according to their ability to form biofilms.

methodsSeventeen participants (average age 17 ± 7 years) were monitored by taking oral rinses and elastomeric ligature samples, and by evaluating the approximal plaque index (API) and gingival bleeding index (GBI) before and after placement of the orthodontic conventional brackets for 12 weeks. Isolated yeasts were counted and biofilm formation was evaluated.

resultsOne hundred and sixteen samples (67 oral rinses and 49 orthodontic elastomers) were collected. Ten patients (58.8% subjects) were Candida-carriers (two were colonized after bracket placement) and C. albicans was the most common species. The average number of yeasts in the oral cavity showed some fluctuation during the study, but in general had an upward trend (adj. R2 = 0.7967, p = 0.07025). A correlation was found between median number of yeasts and the periodontal indices (API, GBI). The average API values decreased in the Candida-carriers (adj. R

conclusionsTreatment with orthodontic appliances promotes Candida yeast colonization, which is variable over time in terms of strain and species, with dominance of C. albicans, and without increased biofilm-forming activity. The API value decreases over time in carriers, and the GBI value increases in uncolonized patients, which may have predictive significance for the development of oral candidiasis during orthodontic treatment.

Indexed as

Oral HygieneOrthodontic BracketsAdolescentAdultCandidaChildDental Plaque IndexHumansPeriodontal IndexPrevalenceYoung AdultCandidaOral hygieneOrthodontic bracketsPeriodontal index

Identifiers

PMID33036600
PMCPMC7547526
OpenAlexW3092008775

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.