Evidence map›Paper›PMID 33036598›Full record

ArticleBMC pulmonary medicine2020

Comorbidities associated with nontuberculous mycobacterial disease in Japanese adults: a claims-data analysis.

Shunsuke Uno, Takanori Asakura, Kozo Morimoto, Kimio Yoshimura, Yoshifumi Uwamino, Tomoyasu Nishimura, Yoshihiko Hoshino, Naoki Hasegawa, Nontuberculous Mycobacteriosis and Bronchiectasis-Japan Research Consortium (NTM-JRC)

Open access · goldAbstract read
In one paragraph

Article in BMC pulmonary medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 46 citations in OpenAlex.

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  19. Asthma Phenotype with Metabolic Dysfunction.Yonsei medical journal · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Shunsuke UnoDepartment of Infectious Diseases, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, Japan.
Takanori AsakuraDivision of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Kozo MorimotoThe Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Tokyo, Japan.
Kimio YoshimuraDepartment of Health Policy and Management, Keio University School of Medicine, Tokyo, Japan.
Yoshifumi UwaminoDepartment of Infectious Diseases, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, Japan.
Tomoyasu NishimuraKeio University Health Center, Tokyo, Japan.
Yoshihiko HoshinoDepartment of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Naoki HasegawaDepartment of Infectious Diseases, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo, Japan. n-hasegawa@z8.keio.jp.ORCID http://orcid.org/0000-0003-0717-7450
Nontuberculous Mycobacteriosis and Bronchiectasis-Japan Research Consortium (NTM-JRC)
Keio University · JPJapan Anti Tuberculosis Association · JPKeio University Hospital · JPNational Institute of Infectious Diseases · JP

Funding

Japan Agency for Medical Research and Development/Japan International Cooperation Agency jp18fk0108064
6 · The paper itself

Abstract

backgroundNontuberculous mycobacterial (NTM) lung disease is one of a growing number of chronic health problems that is difficult to cure in aging societies. While it is important to be vigilant about associated comorbidities in order to provide better patient care, data on the prevalence of comorbidities stratified by country or region are scarce. We aimed to elucidate the comorbidities associated with NTM disease based on Japanese health insurance claims data.

methodsCross-sectional analyses were performed using the claims data for 2014 provided by the Japan Medical Data Center Co., Ltd. Patients aged 20-75 years with ≥3 claims associated with NTM disease were identified and matched to 10 sex-and-age-matched controls that had never made a claim for NTM disease. Thirty-one comorbidities previously suspected to be associated with NTM disease were selected, and the prevalence of these comorbidities compared between cases and controls.

resultOverall, 419 NTM patients (134 males and 285 females) and 4190 non-NTM controls were identified from the JMDC database. Aspergillosis, asthma, chronic heart failure, diffuse panbronchiolitis, gastroesophageal reflux, interstitial pneumonia, lung cancer, cancer other than breast, lung, ovary, or prostate cancer, and rheumatoid arthritis were associated with NTM disease in both males and females. Chronic obstructive pulmonary disease was associated with NTM in males while chronic kidney disease, osteoporosis, and Sjögren syndrome were associated with NTM in females.

conclusionNTM disease was associated with multiple comorbidities that should be considered when providing medical care to individuals with NTM disease.

Indexed as

AdultAgedAnti-Bacterial AgentsCase-Control StudiesComorbidityCross-Sectional StudiesDatabases, FactualFemaleHumansJapanLung DiseasesMaleMiddle AgedMycobacterium Infections, NontuberculousNontuberculous MycobacteriaPrevalenceAnti-Bacterial AgentsClaims-data analysisComorbiditiesNontuberculous mycobacterial diseases

Identifiers

PMID33036598
PMCPMC7547454
OpenAlexW3091882228

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.