Evidence map›Paper›PMID 33036451›Full record

ArticleInternational journal of molecular sciences2020

Allopregnanolone Enhances GABAergic Inhibition in Spinal Motor Networks.

Berthold Drexler, Julia Grenz, Christian Grasshoff, Bernd Antkowiak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Validation of an ELISA kit to measure allopregnanolone in human and equine hair.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Berthold DrexlerExperimental Anesthesiology Section, Department of Anesthesiology and Intensive Care Medicine, Eberhard-Karls-University, Waldhörnlestrasse 22, 72072 Tübingen, Germany.ORCID 0000-0001-7202-1511
Julia GrenzExperimental Anesthesiology Section, Department of Anesthesiology and Intensive Care Medicine, Eberhard-Karls-University, Waldhörnlestrasse 22, 72072 Tübingen, Germany.
Christian GrasshoffExperimental Anesthesiology Section, Department of Anesthesiology and Intensive Care Medicine, Eberhard-Karls-University, Waldhörnlestrasse 22, 72072 Tübingen, Germany.
Bernd AntkowiakExperimental Anesthesiology Section, Department of Anesthesiology and Intensive Care Medicine, Eberhard-Karls-University, Waldhörnlestrasse 22, 72072 Tübingen, Germany.
University of Tübingen · DE

Funding

Deutsche Forschungsgemeinschaft EC 399/3-1
6 · The paper itself

Abstract

The neurosteroid allopregnanolone (ALLO) causes unconsciousness by allosteric modulation of γ-aminobutyric acid type A (GABA

Indexed as

Action PotentialsAnimalsCells, Culturedgamma-Aminobutyric AcidMiceMotor NeuronsNeuromuscular JunctionPregnanolonePropofolReceptors, GABA-ASpinal Cordgamma-Aminobutyric AcidPregnanolonePropofolReceptors, GABA-Aallopregnanoloneelectrophysiologymechanisms of anesthesianeuro-muscular junctionorganotypic culturespropofolspinal networks

Identifiers

PMID33036451
PMCPMC7582554
OpenAlexW3091908870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.