Evidence map›Paper›PMID 33036445›Full record

ArticleJournal of clinical medicine2020

COVID-19 Triage and Test Center: Safety, Feasibility, and Outcomes of Low-Threshold Testing.

Gregory Mansella, Marco Rueegg, Andreas F Widmer, Sarah Tschudin-Sutter, Manuel Battegay, Julia Hoff, Kirstine K Søgaard, Adrian Egli, Bram Stieltjes, Karoline Leuzinger and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Gregory MansellaEmergency Department, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Marco RueeggEmergency Department, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Andreas F WidmerDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Sarah Tschudin-SutterDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Manuel BattegayDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Julia HoffEmergency Department, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Kirstine K SøgaardDivision of Clinical Bacteriology and Mycology, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Adrian EgliDivision of Clinical Bacteriology and Mycology, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Bram StieltjesDepartment of Radiology, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Karoline LeuzingerDivision of Clinical Virology, University Hospital Basel, CH-4031 Basel, Switzerland.
Hans H HirschDivision of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Andrea MeienbergMedical Outpatient Department, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Thilo BurkardMedical Outpatient Department, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Michael MayrMedical Outpatient Department, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.ORCID 0000-0002-1962-8186
Roland BingisserEmergency Department, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.
Christian H NickelEmergency Department, University Hospital Basel, University of Basel, CH-4031 Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This prospective observational study evaluated the safety and feasibility of a low threshold testing process in a Triage and Test Center (TTC) during the early course of the coronavirus disease 19 (COVID-19) pandemic. In addition, we aimed to identify clinical predictors for a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) swab result. Patients underwent informal triage, standardized history taking, and physician evaluation, only where indicated. Patients were observed for 30 days. Safety was the primary outcome and was defined as a COVID-19-related 30 day re-presentation rate <5% and mortality rate <1% in patients presenting to the TTC. Feasibility was defined as an overruling of informal triage <5%. Among 4815 presentations, 572 (11.9%) were tested positive for SARS-CoV-2, and 4774 were discharged. Mortality at 30-days was 0.04% (2 patients, one of which related to COVID-19). Fever (OR 2.03 [95% CI 1.70;2.42]), myalgia (OR 1.94 [1.63;2.31]), chills (OR 1.77 [1.44;2.16]), headache (OR 1.61 [1.34;1.94]), cough (OR 1.50 [1.24;1.83]), weakness (OR 1.46 [1.21;1.76]), and confusion (OR 1.39 [1.06;1.80]) were associated with test positivity. Re-presentation rate was 8% overall and 1.4% in COVID-19 related re-presentation (69 of 4774). The overruling rate of informal triage was 1.5%. According to our study, a low-threshold testing process in a TTC appeared to be safe (low re-presentation and low mortality) and is feasible (low overruling of informal triage). A COVID-19 diagnosis based on clinical parameters only does not appear possible.

Indexed as

COVID-19dispositiondrive-thru testingresource allocationSARS-CoV-2symptomsTriage and Test Center

Identifiers

PMID33036445
PMCPMC7601442

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.