Evidence map›Paper›PMID 33036380›Full record

ArticleInternational journal of molecular sciences2020

Is the secret of VDAC Isoforms in their gene regulation? Characterization of human

Federica Zinghirino, Xena Giada Pappalardo, Angela Messina, Francesca Guarino, Vito De Pinto

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

  1. Pathogens (Basel, Switzerland) · 2026
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  11. VDAC2 and the BCL-2 family of proteins.Biochemical Society transactions · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Federica ZinghirinoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia 64, 95123 Catania, Italy.ORCID 0000-0001-8822-4217
Xena Giada PappalardoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia 64, 95123 Catania, Italy.
Angela MessinaDepartment of Biological, Geological and Environmental Sciences, Section of Molecular Biology, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Francesca GuarinoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia 64, 95123 Catania, Italy.ORCID 0000-0002-0704-7333
Vito De PintoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia 64, 95123 Catania, Italy.ORCID 0000-0001-5513-2906
University of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

VDACs (voltage-dependent anion-selective channels) are pore-forming proteins of the outer mitochondrial membrane, whose permeability is primarily due to VDACs' presence. In higher eukaryotes, three isoforms are raised during the evolution: they have the same exon-intron organization, and the proteins show the same channel-forming activity. We provide a comprehensive analysis of the three human

Indexed as

Gene Expression RegulationAnimalsBase SequenceBinding SitesCell Line, TumorComputational BiologyDatabases, GeneticGene Expression ProfilingHeLa CellsHumansMitochondrial ProteinsMultigene FamilyNucleotide MotifsPromoter Regions, GeneticProtein IsoformsTranscriptional ActivationMitochondrial ProteinsProtein IsoformsTranscription FactorsVoltage-Dependent Anion Channelscore promoterexpression profilegene structuremitochondrial functiontranscription factor binding sitesVDAC isoforms

Identifiers

PMID33036380
PMCPMC7582299
OpenAlexW3092608235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.