Evidence map›Paper›PMID 33036340›Full record

ArticleGeriatrics (Basel, Switzerland)2020

Protein Ingredient in Saliva on Oral Dryness Patients Caused by Calcium Blocker.

Fumi Mizuhashi, Takao Morita, Shuji Toya, Ritsuko Sato, Yuko Watarai, Kaoru Koide

Abstract read
In one paragraph

Article in Geriatrics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fumi MizuhashiDepartment of Removable Prosthodontics, the Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8580, Japan.ORCID 0000-0002-0699-0637
Takao MoritaDepartment of Biochemistry, the Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8580, Japan.
Shuji ToyaDry Mouth Clinic, Oral and Maxillofacial Surgery, The Nippon Dental University Niigata Hospital, Niigata 951-8580, Japan.
Ritsuko SatoDepartment of Biochemistry, the Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8580, Japan.
Yuko WataraiDepartment of Removable Prosthodontics, the Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8580, Japan.
Kaoru KoideDepartment of Removable Prosthodontics, the Nippon Dental University School of Life Dentistry at Niigata, Niigata 951-8580, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral dryness as a side effect of certain drugs is increasing. The aim of this study was to examine the change of the protein ingredient in saliva of oral dryness patients caused by calcium blocker. Six patients taking calcium blocker and six healthy elderly were enrolled. Unstimulated salivary flow rate, protein concentration, and flow rate of protein were measured and compared between the patients taking calcium blocker and healthy elderly. iTRAQ (Isobaric Tag for Relative and Absolute Quantitation) proteomic analysis was performed to extract the salivary protein changed in patient taking calcium blocker, and the intensities of Western blotting products were quantified (unpaired

Indexed as

calcium blockeroral drynessprotein ingredientsaliva

Identifiers

PMID33036340
PMCPMC7709676

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.