Evidence map›Paper›PMID 33036293›Full record

ArticleMolecules (Basel, Switzerland)2020

Clean Grinding Technique: A Facile Synthesis and In Silico Antiviral Activity of Hydrazones, Pyrazoles, and Pyrazines Bearing Thiazole Moiety against SARS-CoV-2 Main Protease (M

Sraa Abu-Melha, Mastoura M Edrees, Sayed M Riyadh, Mohamad R Abdelaziz, Abdo A Elfiky, Sobhi M Gomha

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Green synthesis,Future medicinal chemistry · 2025
    Article
  5. Article
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  7. Article
  8. Article
  9. Article
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  12. Article
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  14. Article
  15. Article
  16. Article
  17. Synthesis and In Silico Study of Some NewCurrent issues in molecular biology · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sraa Abu-MelhaDepartment of Chemistry, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia.ORCID 0000-0001-8949-9204
Mastoura M EdreesDepartment of Chemistry, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia.ORCID 0000-0002-2301-7652
Sayed M RiyadhDepartment of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.
Mohamad R AbdelazizDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, MIU University, Cairo 19648, Egypt.
Abdo A ElfikyBiophysics Department, Faculty of Science, Cairo University, Giza 12613, Egypt.ORCID 0000-0003-4600-6240
Sobhi M GomhaDepartment of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.ORCID 0000-0002-7739-2837

Funding

King Khalid University R.G.P.1/205/41
6 · The paper itself

Abstract

A novel series of some hydrazones bearing thiazole moiety were generated via solvent-drop grinding of thiazole carbohydrazide

Indexed as

Antiviral AgentsBetacoronavirusBinding SitesCoronavirus 3C ProteasesCoronavirus InfectionsCOVID-19Cysteine EndopeptidasesDrug DiscoveryHumansHydrazonesMolecular Docking SimulationMolecular Dynamics SimulationPandemicsPneumonia, ViralProtease InhibitorsProtein BindingAntiviral AgentsCoronavirus 3C ProteasesCysteine EndopeptidasesHydrazonesProtease InhibitorsPyrazinesPyrazolesViral Nonstructural Proteinscondensationcyclo-condensationdockingHydrazidehydrazoneSARS-CoV-2 Mpro

Identifiers

PMID33036293
PMCPMC7582706

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.