Evidence map›Paper›PMID 33036258›Full record

ArticleAntioxidants (Basel, Switzerland)2020

The Preventive Effects of Xanthohumol on Vascular Calcification Induced by Vitamin D

Shu-Fen Liou, Thi Tuyet Ngan Nguyen, Jong-Hau Hsu, Erna Sulistyowati, Shang-En Huang, Bin-Nan Wu, Ming-Chung Lin, Jwu-Lai Yeh

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

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  7. Iron overload impairs renal function and is associated with vascular calcification in rat aorta.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Article
  8. Article
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  15. Antioxidants of Natural Products.Antioxidants (Basel, Switzerland) · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Shu-Fen LiouDepartment of Pharmacy, Chia-Nan University of Pharmacy and Science, Tainan 717, Taiwan.
Thi Tuyet Ngan NguyenGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Jong-Hau HsuGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Erna SulistyowatiGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0003-0805-8154
Shang-En HuangGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Bin-Nan WuGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-6593-5120
Ming-Chung LinDepartment of Anesthesiology, Chi Mei Medical Center, Tainan 710, Taiwan.
Jwu-Lai YehGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.ORCID 0000-0001-7101-5865
Kaohsiung Medical University · TWChia Nan University of Pharmacy and Science · TWChi Mei Medical Center · TWNational Sun Yat-sen University · TW

Funding

Chi-Mei Medical Center and Kaohsiung Medical University Research Foundation 109CM-KMU-011Ministry of Science and Technology, Taiwan 106-2320-B-037-010-MY3Ministry of Science and Technology, Taiwan 107-2320-B-041-001
6 · The paper itself

Abstract

Vascular calcification (VC) is highly prevalent in patients with atherosclerosis, chronic kidney disease, diabetes mellitus, and hypertension. In blood vessels, VC is associated with major adverse cardiovascular events. Xanthohumol (XN), a main prenylated chalcone found in hops, has antioxidant effects to inhibit VC. This study aimed to investigate whether XN attenuates VC through in vivo study. A rat VC model was established by four weeks oral administration of vitamin D

Indexed as

nicotineosteogenic transitionoxidative stressvascular calcificationvitamin D3xanthohumol

Identifiers

PMID33036258
PMCPMC7599490
OpenAlexW3092439568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.