Evidence map›Paper›PMID 33036235›Full record

ArticlePolymers2020

Shape Memory Polymer Foams Synthesized Using Glycerol and Hexanetriol for Enhanced Degradation Resistance.

Sayyeda Marziya Hasan, Grace K Fletcher, Mary Beth Browning Monroe, Mark A Wierzbicki, Landon D Nash, Duncan J Maitland

Abstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sayyeda Marziya HasanShape Memory Medical Inc., Santa Clara, CA 95054, USA.
Grace K FletcherDepartment of Biomedical Engineering, Texas A&M University-Main Campus, College Station, TX 77843, USA.
Mary Beth Browning MonroeDepartment of Biomedical Engineering, Texas A&M University-Main Campus, College Station, TX 77843, USA.ORCID 0000-0003-4540-5303
Mark A WierzbickiDepartment of Biomedical Engineering, Texas A&M University-Main Campus, College Station, TX 77843, USA.
Landon D NashShape Memory Medical Inc., Santa Clara, CA 95054, USA.
Duncan J MaitlandShape Memory Medical Inc., Santa Clara, CA 95054, USA.ORCID 0000-0001-7001-3761

Funding

National Institute of Neurological Diseases and Stroke Cooperative Program in Translational Research U01NS089692
6 · The paper itself

Abstract

Shape memory polymer foams have been used in a wide range of medical applications, including, but not limited to, vessel occlusion and aneurysm treatment. This unique polymer system has been proven to shape-fill a void, which makes it useful for occlusion applications. While the shape memory polymer foam has superior performance and healing outcomes compared to its leading competitors, some device applications may benefit from longer material degradation times, or degradation-resistant formulations with increased fibrous encapsulation. In this study, biostable shape memory polymer foams were synthesized, and their physical and chemical properties were characterized as an initial evaluation of feasibility for vascular occlusion applications. After characterizing their shape memory behavior in an aqueous environment, degradation of this polymer system was studied in vitro using accelerated oxidative and hydrolytic solutions. Results indicated that the foams did not lose mass under oxidative or hydrolytic conditions, and they maintained high shape recovery in aqueous in vitro models. These degradation-resistant systems have potential for use in vascular occlusion and other wound healing applications that benefit from permanent, space-filling shape memory behavior.

Indexed as

degradation-resistantpolyurethane foamshape memory polymer

Identifiers

PMID33036235
PMCPMC7600845

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.